Affinity Data by PubMed id=23685178

PubMed code 23685178

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50436164 (CHEMBL2398352) Show SMILES CN1C(=O)NC(=O)\C1=C/c1c[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha1 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50436165 (CHEMBL2398351) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha1 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50436164 (CHEMBL2398352) Show SMILES CN1C(=O)NC(=O)\C1=C/c1c[nH]c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50436166 (CHEMBL2398350) Show SMILES CN1C(=O)N(C)\C(=C\c2c[nH]c3ccccc23)C1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50436166 (CHEMBL2398350) Show SMILES CN1C(=O)N(C)\C(=C\c2c[nH]c3ccccc23)C1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha1 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50436165 (CHEMBL2398351) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...				Bioorg Med Chem 21: 4420-5 (2013) Article DOI: 10.1016/j.bmc.2013.04.061 BindingDB Entry DOI: 10.7270/Q2XD132N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%