Affinity Data by PubMed id=23707920

PubMed code 23707920

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM52755 (MLS001004059 \| N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of Aurora A kinase (unknown origin) by Z'-LYTE kinase assay				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
Fudan University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM52755 (MLS001004059 \| N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of Aurora B kinase (unknown origin) by Z'-LYTE kinase assay				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
Fudan University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM52755 (MLS001004059 \| N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant Aurora B kinase (unknown origin) expressed in Escherichia coli				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
Fudan University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%