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PubMed code 23927971

Compile data set for download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 4.5n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493127
PNG
(CHEMBL2417762)
Show SMILES CN1N=C(CC1c1ccc(C)cc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C17H18N2/c1-13-8-10-15(11-9-13)17-12-16(18-19(17)2)14-6-4-3-5-7-14/h3-11,17H,12H2,1-2H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r|
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493116
PNG
(CHEMBL2417758)
Show SMILES CN1N=C(CC1c1cccc(F)c1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-8-5-9-14(17)10-13)11-15(18-19)12-6-3-2-4-7-12/h2-10,16H,11H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493124
PNG
(CHEMBL2417761)
Show SMILES CN1N=C(CC1c1cccc(C)c1)c1ccccc1 |c:2|
Show InChI InChI=1S/C17H18N2/c1-13-7-6-10-15(11-13)17-12-16(18-19(17)2)14-8-4-3-5-9-14/h3-11,17H,12H2,1-2H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493129
PNG
(CHEMBL2417760)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccccc1 |c:2|
Show InChI InChI=1S/C17H18N2/c1-13-8-6-7-11-15(13)17-12-16(18-19(17)2)14-9-4-3-5-10-14/h3-11,17H,12H2,1-2H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493123
PNG
(CHEMBL2417756)
Show SMILES CN1N=C(CC1c1ccccc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H16N2/c1-18-16(14-10-6-3-7-11-14)12-15(17-18)13-8-4-2-5-9-13/h2-11,16H,12H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493115
PNG
(CHEMBL2417759)
Show SMILES CN1N=C(CC1c1ccc(F)cc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-7-9-14(17)10-8-13)11-15(18-19)12-5-3-2-4-6-12/h2-10,16H,11H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493105
PNG
(CHEMBL2417754)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(10-3-2-4-11(17)7-10)9-14(18-19)13-6-5-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493128
PNG
(CHEMBL2417757)
Show SMILES CN1N=C(CC1c1ccccc1F)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-9-5-6-10-14(13)17)11-15(18-19)12-7-3-2-4-8-12/h2-10,16H,11H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493118
PNG
(CHEMBL2417753)
Show SMILES CN1N=C(CC1c1ccccc1Cl)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(11-4-2-3-5-13(11)17)9-14(18-19)12-7-6-10(20)8-16(12)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493117
PNG
(CHEMBL2417755)
Show SMILES CN1N=C(CC1c1ccc(Cl)cc1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(10-2-4-11(17)5-3-10)9-14(18-19)13-7-6-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493105
PNG
(CHEMBL2417754)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(10-3-2-4-11(17)7-10)9-14(18-19)13-6-5-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493119
PNG
(CHEMBL2417749)
Show SMILES CN1N=C(CC1c1ccc(F)cc1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15FN2O2/c1-19-15(10-2-4-11(17)5-3-10)9-14(18-19)13-7-6-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493119
PNG
(CHEMBL2417749)
Show SMILES CN1N=C(CC1c1ccc(F)cc1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15FN2O2/c1-19-15(10-2-4-11(17)5-3-10)9-14(18-19)13-7-6-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493113
PNG
(CHEMBL2417764)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15ClN2/c1-19-16(13-8-5-9-14(17)10-13)11-15(18-19)12-6-3-2-4-7-12/h2-10,16H,11H2,1H3
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Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493118
PNG
(CHEMBL2417753)
Show SMILES CN1N=C(CC1c1ccccc1Cl)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(11-4-2-3-5-13(11)17)9-14(18-19)12-7-6-10(20)8-16(12)21/h2-8,15,20-21H,9H2,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493117
PNG
(CHEMBL2417755)
Show SMILES CN1N=C(CC1c1ccc(Cl)cc1)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15ClN2O2/c1-19-15(10-2-4-11(17)5-3-10)9-14(18-19)13-7-6-12(20)8-16(13)21/h2-8,15,20-21H,9H2,1H3
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n/an/a 1.39E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493127
PNG
(CHEMBL2417762)
Show SMILES CN1N=C(CC1c1ccc(C)cc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C17H18N2/c1-13-8-10-15(11-9-13)17-12-16(18-19(17)2)14-6-4-3-5-7-14/h3-11,17H,12H2,1-2H3
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n/an/a 1.39E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493123
PNG
(CHEMBL2417756)
Show SMILES CN1N=C(CC1c1ccccc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H16N2/c1-18-16(14-10-6-3-7-11-14)12-15(17-18)13-8-4-2-5-9-13/h2-11,16H,12H2,1H3
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n/an/a 1.68E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493116
PNG
(CHEMBL2417758)
Show SMILES CN1N=C(CC1c1cccc(F)c1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-8-5-9-14(17)10-13)11-15(18-19)12-6-3-2-4-7-12/h2-10,16H,11H2,1H3
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n/an/a 1.82E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493109
PNG
(CHEMBL2417772)
Show SMILES CN1N=C(CC1c1ccc(C)cc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-3-5-14(6-4-12)17-11-16(18-19(17)2)13-7-9-15(20)10-8-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 1.91E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493106
PNG
(CHEMBL2417750)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C17H18N2O2/c1-11-5-3-4-6-13(11)16-10-15(18-19(16)2)14-8-7-12(20)9-17(14)21/h3-9,16,20-21H,10H2,1-2H3
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n/an/a 2.04E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493108
PNG
(CHEMBL2417774)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(12-3-2-4-13(17)9-12)10-15(18-19)11-5-7-14(20)8-6-11/h2-9,16,20H,10H2,1H3
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n/an/a 2.07E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493120
PNG
(CHEMBL2417775)
Show SMILES CN1N=C(CC1c1ccc(Cl)cc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(12-2-6-13(17)7-3-12)10-15(18-19)11-4-8-14(20)9-5-11/h2-9,16,20H,10H2,1H3
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n/an/a 2.64E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493128
PNG
(CHEMBL2417757)
Show SMILES CN1N=C(CC1c1ccccc1F)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-9-5-6-10-14(13)17)11-15(18-19)12-7-3-2-4-8-12/h2-10,16H,11H2,1H3
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n/an/a 2.84E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493115
PNG
(CHEMBL2417759)
Show SMILES CN1N=C(CC1c1ccc(F)cc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15FN2/c1-19-16(13-7-9-14(17)10-8-13)11-15(18-19)12-5-3-2-4-6-12/h2-10,16H,11H2,1H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493112
PNG
(CHEMBL2417767)
Show SMILES CN1N=C(CC1c1ccccc1F)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15FN2O/c1-19-16(13-4-2-3-5-14(13)17)10-15(18-19)11-6-8-12(20)9-7-11/h2-9,16,20H,10H2,1H3
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n/an/a 3.04E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493130
PNG
(CHEMBL2417768)
Show SMILES CN1N=C(CC1c1cccc(F)c1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15FN2O/c1-19-16(12-3-2-4-13(17)9-12)10-15(18-19)11-5-7-14(20)8-6-11/h2-9,16,20H,10H2,1H3
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n/an/a 3.17E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493129
PNG
(CHEMBL2417760)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccccc1 |c:2|
Show InChI InChI=1S/C17H18N2/c1-13-8-6-7-11-15(13)17-12-16(18-19(17)2)14-9-4-3-5-10-14/h3-11,17H,12H2,1-2H3
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n/an/a 3.26E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493111
PNG
(CHEMBL2417769)
Show SMILES CN1N=C(CC1c1ccc(F)cc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15FN2O/c1-19-16(12-2-6-13(17)7-3-12)10-15(18-19)11-4-8-14(20)9-5-11/h2-9,16,20H,10H2,1H3
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n/an/a 3.65E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493114
PNG
(CHEMBL2417763)
Show SMILES CN1N=C(CC1c1ccccc1Cl)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15ClN2/c1-19-16(13-9-5-6-10-14(13)17)11-15(18-19)12-7-3-2-4-8-12/h2-10,16H,11H2,1H3
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n/an/a 3.65E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493107
PNG
(CHEMBL2417747)
Show SMILES CN1N=C(CC1c1ccccc1F)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C16H15FN2O2/c1-19-15(11-4-2-3-5-13(11)17)9-14(18-19)12-7-6-10(20)8-16(12)21/h2-8,15,20-21H,9H2,1H3
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n/an/a 3.87E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493125
PNG
(CHEMBL2417765)
Show SMILES CN1N=C(CC1c1ccc(Cl)cc1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15ClN2/c1-19-16(13-7-9-14(17)10-8-13)11-15(18-19)12-5-3-2-4-6-12/h2-10,16H,11H2,1H3
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n/an/a 3.95E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493106
PNG
(CHEMBL2417750)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccc(O)cc1O |c:2|
Show InChI InChI=1S/C17H18N2O2/c1-11-5-3-4-6-13(11)16-10-15(18-19(16)2)14-8-7-12(20)9-17(14)21/h3-9,16,20-21H,10H2,1-2H3
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n/an/a 3.98E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493122
PNG
(CHEMBL2417771)
Show SMILES CN1N=C(CC1c1cccc(C)c1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-4-3-5-14(10-12)17-11-16(18-19(17)2)13-6-8-15(20)9-7-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 5.78E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM29136
PNG
(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Show SMILES CC(C)NNC(=O)c1ccncc1
Show InChI InChI=1S/C9H13N3O/c1-7(2)11-12-9(13)8-3-5-10-6-4-8/h3-7,11H,1-2H3,(H,12,13)
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n/an/a 6.56E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM29136
PNG
(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Show SMILES CC(C)NNC(=O)c1ccncc1
Show InChI InChI=1S/C9H13N3O/c1-7(2)11-12-9(13)8-3-5-10-6-4-8/h3-7,11H,1-2H3,(H,12,13)
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n/an/a 7.54E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493109
PNG
(CHEMBL2417772)
Show SMILES CN1N=C(CC1c1ccc(C)cc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-3-5-14(6-4-12)17-11-16(18-19(17)2)13-7-9-15(20)10-8-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 9.13E+3n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493121
PNG
(CHEMBL2417773)
Show SMILES CN1N=C(CC1c1ccccc1Cl)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(13-4-2-3-5-14(13)17)10-15(18-19)11-6-8-12(20)9-7-11/h2-9,16,20H,10H2,1H3
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n/an/a 1.04E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493121
PNG
(CHEMBL2417773)
Show SMILES CN1N=C(CC1c1ccccc1Cl)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(13-4-2-3-5-14(13)17)10-15(18-19)11-6-8-12(20)9-7-11/h2-9,16,20H,10H2,1H3
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n/an/a 1.18E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493120
PNG
(CHEMBL2417775)
Show SMILES CN1N=C(CC1c1ccc(Cl)cc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(12-2-6-13(17)7-3-12)10-15(18-19)11-4-8-14(20)9-5-11/h2-9,16,20H,10H2,1H3
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n/an/a 1.27E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493122
PNG
(CHEMBL2417771)
Show SMILES CN1N=C(CC1c1cccc(C)c1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-4-3-5-14(10-12)17-11-16(18-19(17)2)13-6-8-15(20)9-7-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 1.63E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493108
PNG
(CHEMBL2417774)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H15ClN2O/c1-19-16(12-3-2-4-13(17)9-12)10-15(18-19)11-5-7-14(20)8-6-11/h2-9,16,20H,10H2,1H3
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n/an/a 1.87E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493110
PNG
(CHEMBL2417770)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-5-3-4-6-15(12)17-11-16(18-19(17)2)13-7-9-14(20)10-8-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 2.01E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493110
PNG
(CHEMBL2417770)
Show SMILES CN1N=C(CC1c1ccccc1C)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C17H18N2O/c1-12-5-3-4-6-15(12)17-11-16(18-19(17)2)13-7-9-14(20)10-8-13/h3-10,17,20H,11H2,1-2H3
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n/an/a 2.19E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50493126
PNG
(CHEMBL2417766)
Show SMILES CN1N=C(CC1c1ccccc1)c1ccc(O)cc1 |c:2|
Show InChI InChI=1S/C16H16N2O/c1-18-16(13-5-3-2-4-6-13)11-15(17-18)12-7-9-14(19)10-8-12/h2-10,16,19H,11H2,1H3
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n/an/a 2.68E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50493113
PNG
(CHEMBL2417764)
Show SMILES CN1N=C(CC1c1cccc(Cl)c1)c1ccccc1 |c:2|
Show InChI InChI=1S/C16H15ClN2/c1-19-16(13-8-5-9-14(17)10-13)11-15(18-19)12-6-3-2-4-7-12/h2-10,16H,11H2,1H3
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n/an/a 5.10E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 6.14E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r|
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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n/an/a 6.73E+4n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM15613
PNG
(4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-ch...)
Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)
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n/an/a 3.61E+5n/an/an/an/an/an/a



Universit£ La Sapienza

Curated by ChEMBL


Assay Description
Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...

Bioorg Med Chem Lett 23: 5128-30 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.035
BindingDB Entry DOI: 10.7270/Q2WD43H9
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%