Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent GABA transporter 1 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin... | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of EAAT2 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio... | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of EAAT3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio... | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent GABA transporter 3 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of GAT-3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin... | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of EAAT1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio... | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50218812 ((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Inhibition of GlyT1 (unknown origin) expressed in MDCK cells using [3H]-glycine as substrate after 10 mins by scintillation counting | J Nat Prod 76: 1889-95 (2013) Article DOI: 10.1021/np400452n BindingDB Entry DOI: 10.7270/Q2805413 | |||||||||||
More data for this Ligand-Target Pair |