Affinity Data by PubMed id=24165164

PubMed code 24165164

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108063 (2‐({4‐[(3‐ aminopropyl)(benzyl)a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+4	-29.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108061 (Nor-lapachol) Show SMILES CC(C)C=C1C(=O)C(=O)c2ccccc2C1=O \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.80E+4	-28.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108062 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+4	-27.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108063 (2‐({4‐[(3‐ aminopropyl)(benzyl)a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80E+4	-27.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108061 (Nor-lapachol) Show SMILES CC(C)C=C1C(=O)C(=O)c2ccccc2C1=O \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+4	-26.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108062 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+4	-26.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108064 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.80E+4	-25.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108060 (4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-di...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.90E+4	-25.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108064 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30E+4	-24.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%