BindingDB logo
myBDB logout

PubMed code 24295046

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 2


(Homo sapiens (Human))		BDBM50446539
PNG
(CHEMBL3110144)
Show SMILES Cc1nn(-c2ccc(Cl)cc2Cl)c2c1c1C(=O)NC(=O)c1c1cccn21
Show InChI InChI=1S/C18H10Cl2N4O2/c1-8-13-15-14(16(25)21-17(15)26)12-3-2-6-23(12)18(13)24(22-8)11-5-4-9(19)7-10(11)20/h2-7H,1H3,(H,21,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Universit£ di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK2 using ATP/Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay

J Med Chem 56: 10066-78 (2013)


Article DOI: 10.1021/jm401466v
BindingDB Entry DOI: 10.7270/Q2NC62PC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%