Affinity Data by PubMed id=24387325

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
G-protein coupled bile acid receptor 1 (Homo sapiens (Human))	BDBM50011369 (CHEMBL3260994) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Transactivation of human GP-BAR1 transfected in HEK293T cells assessed as induction of intracellular cAMP production after 18 hrs by cAMP responsive ...				J Med Chem 57: 937-54 (2014) Article DOI: 10.1021/jm401873d BindingDB Entry DOI: 10.7270/Q2RR20S3
Istituto Italiano di Tecnologia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50011369 (CHEMBL3260994) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Transactivation of human FXR transfected in human HepG2 cells by beta-galactosidase reporter gene assay				J Med Chem 57: 937-54 (2014) Article DOI: 10.1021/jm401873d BindingDB Entry DOI: 10.7270/Q2RR20S3
Istituto Italiano di Tecnologia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%