Found 4 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50011472
(CHEMBL3261266)Show SMILES COc1cc(OC)c(\C=C\S(=O)(=O)Cc2cnc(OC)c(NS(C)(=O)=O)c2)c(OC)c1 Show InChI InChI=1S/C19H24N2O8S2/c1-26-14-9-17(27-2)15(18(10-14)28-3)6-7-31(24,25)12-13-8-16(21-30(5,22)23)19(29-4)20-11-13/h6-11,21H,12H2,1-5H3/b7-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells |
J Med Chem 57: 2275-91 (2014)
Article DOI: 10.1021/jm4019614
BindingDB Entry DOI: 10.7270/Q2H70HBC |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50011473
(CHEMBL3261277)Show SMILES COc1cc(OC)c(\C=C\S(=O)(=O)Cc2ccc(OC)c(NS(C)(=O)=O)n2)c(OC)c1 Show InChI InChI=1S/C19H24N2O8S2/c1-26-14-10-17(28-3)15(18(11-14)29-4)8-9-31(24,25)12-13-6-7-16(27-2)19(20-13)21-30(5,22)23/h6-11H,12H2,1-5H3,(H,20,21)/b9-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells |
J Med Chem 57: 2275-91 (2014)
Article DOI: 10.1021/jm4019614
BindingDB Entry DOI: 10.7270/Q2H70HBC |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50011471
(CHEMBL3261276)Show SMILES COc1cc(OC)c(\C=C\S(=O)(=O)Cc2ccc(OC)c(N)n2)c(OC)c1 Show InChI InChI=1S/C18H22N2O6S/c1-23-13-9-16(25-3)14(17(10-13)26-4)7-8-27(21,22)11-12-5-6-15(24-2)18(19)20-12/h5-10H,11H2,1-4H3,(H2,19,20)/b8-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells |
J Med Chem 57: 2275-91 (2014)
Article DOI: 10.1021/jm4019614
BindingDB Entry DOI: 10.7270/Q2H70HBC |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50011470
(CHEMBL3261265)Show SMILES COc1cc(OC)c(\C=C\S(=O)(=O)Cc2cnc(OC)c(N)c2)c(OC)c1 Show InChI InChI=1S/C18H22N2O6S/c1-23-13-8-16(24-2)14(17(9-13)25-3)5-6-27(21,22)11-12-7-15(19)18(26-4)20-10-12/h5-10H,11,19H2,1-4H3/b6-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells |
J Med Chem 57: 2275-91 (2014)
Article DOI: 10.1021/jm4019614
BindingDB Entry DOI: 10.7270/Q2H70HBC |
More data for this
Ligand-Target Pair | |
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