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PubMed code 24491635

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor Jun


(Homo sapiens (Human))
BDBM50446664
PNG
(CHEMBL3113338)
Show SMILES OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1)C(=O)O[C@H](Cc1ccc(O)c(O)c1)C(O)=O |r|
Show InChI InChI=1S/C36H32O16/c37-19-5-1-15(9-23(19)41)11-27(33(45)46)51-35(49)31-29(17-3-7-21(39)25(43)13-17)30(18-4-8-22(40)26(44)14-18)32(31)36(50)52-28(34(47)48)12-16-2-6-20(38)24(42)10-16/h1-10,13-14,27-32,37-44H,11-12H2,(H,45,46)(H,47,48)/t27-,28-,29-,30-,31-,32-/m1/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



National Defense Medical Center, Taiwan

Curated by ChEMBL


Assay Description
Inhibition of transcription factor AP-1 binding to oligonucleotide containing TPA-responsive element in TPA-activated human HeLa cells after 1 hr by ...


Bioorg Med Chem 22: 1766-72 (2014)


Article DOI: 10.1016/j.bmc.2014.01.009
BindingDB Entry DOI: 10.7270/Q2ZP47K7
More data for this
Ligand-Target Pair
Transcription factor Jun


(Homo sapiens (Human))
BDBM50446663
PNG
(CHEMBL3113339)
Show SMILES OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)C1C(C(=Cc2ccc(O)c(O)c12)C(=O)O[C@H](Cc1ccc(O)c(O)c1)C(O)=O)c1ccc(O)c(O)c1 |r,c:19|
Show InChI InChI=1S/C36H30O16/c37-20-5-1-15(9-24(20)41)11-27(33(45)46)51-35(49)19-13-17-4-8-23(40)32(44)30(17)31(29(19)18-3-7-22(39)26(43)14-18)36(50)52-28(34(47)48)12-16-2-6-21(38)25(42)10-16/h1-10,13-14,27-29,31,37-44H,11-12H2,(H,45,46)(H,47,48)/t27-,28-,29?,31?/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



National Defense Medical Center, Taiwan

Curated by ChEMBL


Assay Description
Inhibition of transcription factor AP-1 binding to oligonucleotide containing TPA-responsive element in TPA-activated human HeLa cells after 1 hr by ...


Bioorg Med Chem 22: 1766-72 (2014)


Article DOI: 10.1016/j.bmc.2014.01.009
BindingDB Entry DOI: 10.7270/Q2ZP47K7
More data for this
Ligand-Target Pair
Transcription factor Jun


(Homo sapiens (Human))
BDBM50446665
PNG
(CHEMBL3112597)
Show SMILES OC(C(\C(=C\c1ccc(O)c(O)c1)C(O)=O)c1ccc(O)c(O)c1)C(O)=O
Show InChI InChI=1S/C18H16O9/c19-11-3-1-8(6-13(11)21)5-10(17(24)25)15(16(23)18(26)27)9-2-4-12(20)14(22)7-9/h1-7,15-16,19-23H,(H,24,25)(H,26,27)/b10-5-
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n/an/a 1.19E+4n/an/an/an/an/an/a



National Defense Medical Center, Taiwan

Curated by ChEMBL


Assay Description
Inhibition of transcription factor AP-1 binding to oligonucleotide containing TPA-responsive element in TPA-activated human HeLa cells after 1 hr by ...


Bioorg Med Chem 22: 1766-72 (2014)


Article DOI: 10.1016/j.bmc.2014.01.009
BindingDB Entry DOI: 10.7270/Q2ZP47K7
More data for this
Ligand-Target Pair
Transcription factor Jun


(Homo sapiens (Human))
BDBM50133496
PNG
((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...)
Show SMILES OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c1ccc(O)c(O)c1 |r|
Show InChI InChI=1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
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Similars

Article
PubMed
n/an/a 1.62E+4n/an/an/an/an/an/a



National Defense Medical Center, Taiwan

Curated by ChEMBL


Assay Description
Inhibition of transcription factor AP-1 binding to oligonucleotide containing TPA-responsive element in TPA-activated human HeLa cells after 1 hr by ...


Bioorg Med Chem 22: 1766-72 (2014)


Article DOI: 10.1016/j.bmc.2014.01.009
BindingDB Entry DOI: 10.7270/Q2ZP47K7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%