Affinity Data by PubMed id=24675175

PubMed code 24675175

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074501 (Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
South Dakota State University Curated by ChEMBL					Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...				Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K
South Dakota State University Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50003912 (CHEMBL3235706) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
South Dakota State University Curated by ChEMBL					Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...				Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K
South Dakota State University Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50003909 (CHEMBL3235700) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
South Dakota State University Curated by ChEMBL					Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...				Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K
South Dakota State University Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50003910 (CHEMBL3235703) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
South Dakota State University Curated by ChEMBL					Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...				Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K
South Dakota State University Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50003911 (CHEMBL3235705) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
South Dakota State University Curated by ChEMBL					Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...				Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K
South Dakota State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%