Affinity Data by PubMed id=24731278

PubMed code 24731278

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholinesterase (Equus caballus (Horse))	BDBM50400024 (CHEMBL2177719) Show SMILES CCN(C)C(=O)Oc1cccc2NCC(CCN)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50400020 (CHEMBL2181475) Show SMILES CCN(C)C(=O)Oc1cccc2NCC(CCC(=O)OC)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013328 (CHEMBL3263347) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2NCC(CCN(C)C)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50400024 (CHEMBL2177719) Show SMILES CCN(C)C(=O)Oc1cccc2NCC(CCN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50400027 (CHEMBL2177716) Show SMILES CCN(C)C(=O)Oc1cccc2N(CCC(=O)OC)CCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013334 (CHEMBL3263351) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2N(CCCN(C)C)CCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013332 (CHEMBL3263349) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2NCC(CCCN)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013328 (CHEMBL3263347) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2NCC(CCN(C)C)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013332 (CHEMBL3263349) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2NCC(CCCN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013331 (CHEMBL3263348) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2C(CCN(C)C)CNc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013334 (CHEMBL3263351) Show SMILES Cl.CCN(C)C(=O)Oc1cccc2N(CCCN(C)C)CCc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50400009 (CHEMBL2177708) Show SMILES CCN(C)C(=O)Oc1ccc2C(CCC(=O)OC)CNc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013382 (CHEMBL3263352) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2CCN(CCCN(C)C)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50013333 (CHEMBL3263350) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2C(CCCN)CNc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50400027 (CHEMBL2177716) Show SMILES CCN(C)C(=O)Oc1cccc2N(CCC(=O)OC)CCc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50400025 (CHEMBL2177718) Show SMILES CCN(C)C(=O)Oc1ccc2CCN(CCC(=O)OC)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50400020 (CHEMBL2181475) Show SMILES CCN(C)C(=O)Oc1cccc2NCC(CCC(=O)OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013331 (CHEMBL3263348) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2C(CCN(C)C)CNc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013333 (CHEMBL3263350) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2C(CCCN)CNc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50013382 (CHEMBL3263352) Show SMILES Cl.CCN(C)C(=O)Oc1ccc2CCN(CCCN(C)C)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50400009 (CHEMBL2177708) Show SMILES CCN(C)C(=O)Oc1ccc2C(CCC(=O)OC)CNc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM50400025 (CHEMBL2177718) Show SMILES CCN(C)C(=O)Oc1ccc2CCN(CCC(=O)OC)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 24: 2283-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.081 BindingDB Entry DOI: 10.7270/Q21V5GHZ
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%