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PubMed code 24792812

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 1-alpha/beta


(Homo sapiens (Human))
BDBM50016098
PNG
(CHEMBL3261195)
Show SMILES [H][C@@]12[C@H](OC(=O)CCCCC)C=C3COC(=O)C3(O)[C@@]1(C)CCCC2(C)C |r,t:11|
Show InChI InChI=1S/C21H32O5/c1-5-6-7-9-16(22)26-15-12-14-13-25-18(23)21(14,24)20(4)11-8-10-19(2,3)17(15)20/h12,15,17,24H,5-11,13H2,1-4H3/t15-,17+,20+,21?/m1/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.18E+4n/an/an/an/an/an/a



Institute of Biotechnology and Drug Research (IBWF)

Curated by ChEMBL


Assay Description
Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 ...


Bioorg Med Chem 22: 2912-8 (2014)


Article DOI: 10.1016/j.bmc.2014.04.015
BindingDB Entry DOI: 10.7270/Q21J9CBW
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 1-alpha/beta


(Homo sapiens (Human))
BDBM50016099
PNG
(CHEMBL3261196)
Show SMILES [H][C@@]12[C@H](OC(=O)CCCCC)C=C3COC(=O)[C@]3(O)[C@@]1(C)[C@H](O)CCC2(C)C |r,t:11|
Show InChI InChI=1S/C21H32O6/c1-5-6-7-8-16(23)27-14-11-13-12-26-18(24)21(13,25)20(4)15(22)9-10-19(2,3)17(14)20/h11,14-15,17,22,25H,5-10,12H2,1-4H3/t14-,15-,17+,20+,21+/m1/s1
PDB
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KEGG

UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.07E+4n/an/an/an/an/an/a



Institute of Biotechnology and Drug Research (IBWF)

Curated by ChEMBL


Assay Description
Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 ...


Bioorg Med Chem 22: 2912-8 (2014)


Article DOI: 10.1016/j.bmc.2014.04.015
BindingDB Entry DOI: 10.7270/Q21J9CBW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%