Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM16673
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Binding affinity to B-RAF kinase (unknown origin) |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM16673
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Competitive binding affinity to B-RAF kinase (unknown origin) after 60 to 120 mins by FRET analysis |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019451
(CHEMBL3290688)Show SMILES Cl.NC(=N)Nc1cccc(Cc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C21H22N6.ClH/c22-20(23)25-19-8-4-5-16(14-19)13-15-9-11-18(12-10-15)27-21(24)26-17-6-2-1-3-7-17;/h1-12,14H,13H2,(H4,22,23,25)(H3,24,26,27);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019453
(CHEMBL3290690)Show SMILES Cl.NC(=N)Nc1ccc(Oc2cccc(NC(=N)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C20H20N6O.ClH/c21-19(22)24-15-9-11-17(12-10-15)27-18-8-4-7-16(13-18)26-20(23)25-14-5-2-1-3-6-14;/h1-13H,(H4,21,22,24)(H3,23,25,26);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019459
(CHEMBL3290694)Show SMILES Cl.NC(=N)Nc1cccc(Cc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H20ClF3N6.ClH/c23-19-9-8-17(12-18(19)22(24,25)26)32-21(29)31-15-6-4-13(5-7-15)10-14-2-1-3-16(11-14)30-20(27)28;/h1-9,11-12H,10H2,(H4,27,28,30)(H3,29,31,32);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019436
(CHEMBL3290699)Show SMILES Cl.CC(=O)Nc1cccc(Nc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H19ClF3N5O.ClH/c1-13(32)28-16-3-2-4-17(11-16)29-14-5-7-15(8-6-14)30-21(27)31-18-9-10-20(23)19(12-18)22(24,25)26;/h2-12,29H,1H3,(H,28,32)(H3,27,30,31);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019441
(CHEMBL3290431)Show InChI InChI=1S/C14H16N6O.ClH/c15-13(16)19-9-4-6-11(7-5-9)21-12-3-1-2-10(8-12)20-14(17)18;/h1-8H,(H4,15,16,19)(H4,17,18,20);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019442
(CHEMBL3290432)Show InChI InChI=1S/C15H16N6O.ClH/c16-14(17)20-11-6-4-9(5-7-11)13(22)10-2-1-3-12(8-10)21-15(18)19;/h1-8H,(H4,16,17,20)(H4,18,19,21);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019446
(CHEMBL3290435)Show SMILES Cl.C1CN=C(Nc2ccc(Oc3cccc(NC4=NCCN4)c3)cc2)N1 |t:2,16| Show InChI InChI=1S/C18H20N6O.ClH/c1-2-14(24-18-21-10-11-22-18)12-16(3-1)25-15-6-4-13(5-7-15)23-17-19-8-9-20-17;/h1-7,12H,8-11H2,(H2,19,20,23)(H2,21,22,24);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019452
(CHEMBL3290689)Show SMILES Cl.NC(=N)Nc1cccc(Nc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C20H21N7.ClH/c21-19(22)25-18-8-4-7-17(13-18)24-15-9-11-16(12-10-15)27-20(23)26-14-5-2-1-3-6-14;/h1-13,24H,(H4,21,22,25)(H3,23,26,27);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019428
(CHEMBL3290696)Show SMILES Cl.NC(=N)Nc1ccc(Oc2cccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)cc1 Show InChI InChI=1S/C21H18ClF3N6O.ClH/c22-18-9-6-14(11-17(18)21(23,24)25)31-20(28)30-13-2-1-3-16(10-13)32-15-7-4-12(5-8-15)29-19(26)27;/h1-11H,(H4,26,27,29)(H3,28,30,31);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019445
(CHEMBL3290434)Show InChI InChI=1S/C14H17N7.ClH/c15-13(16)20-10-6-4-9(5-7-10)19-11-2-1-3-12(8-11)21-14(17)18;/h1-8,19H,(H4,15,16,20)(H4,17,18,21);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019452
(CHEMBL3290689)Show SMILES Cl.NC(=N)Nc1cccc(Nc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C20H21N7.ClH/c21-19(22)25-18-8-4-7-17(13-18)24-15-9-11-16(12-10-15)27-20(23)26-14-5-2-1-3-6-14;/h1-13,24H,(H4,21,22,25)(H3,23,26,27);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019454
(CHEMBL3290691)Show SMILES Cl.NC(=N)Nc1ccc(Cc2cccc(NC(=N)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C21H22N6.ClH/c22-20(23)25-18-11-9-15(10-12-18)13-16-5-4-8-19(14-16)27-21(24)26-17-6-2-1-3-7-17;/h1-12,14H,13H2,(H4,22,23,25)(H3,24,26,27);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019455
(CHEMBL3290692)Show SMILES Cl.NC(=N)Nc1cccc(Oc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C21H18ClF3N6O.ClH/c22-18-9-6-14(11-17(18)21(23,24)25)31-20(28)30-12-4-7-15(8-5-12)32-16-3-1-2-13(10-16)29-19(26)27;/h1-11H,(H4,26,27,29)(H3,28,30,31);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019437
(CHEMBL3290430)Show InChI InChI=1S/C14H16N6O.ClH/c15-13(16)19-9-1-5-11(6-2-9)21-12-7-3-10(4-8-12)20-14(17)18;/h1-8H,(H4,15,16,19)(H4,17,18,20);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019449
(CHEMBL3290438)Show SMILES Cl.NC(=N)Nc1cccc(Oc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C20H20N6O.ClH/c21-19(22)24-16-7-4-8-18(13-16)27-17-11-9-15(10-12-17)26-20(23)25-14-5-2-1-3-6-14;/h1-13H,(H4,21,22,24)(H3,23,25,26);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019454
(CHEMBL3290691)Show SMILES Cl.NC(=N)Nc1ccc(Cc2cccc(NC(=N)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C21H22N6.ClH/c22-20(23)25-18-11-9-15(10-12-18)13-16-5-4-8-19(14-16)27-21(24)26-17-6-2-1-3-7-17;/h1-12,14H,13H2,(H4,22,23,25)(H3,24,26,27);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019429
(CHEMBL3290697)Show SMILES Cl.NC(=N)Nc1ccc(Cc2cccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)cc1 Show InChI InChI=1S/C22H20ClF3N6.ClH/c23-19-9-8-17(12-18(19)22(24,25)26)32-21(29)31-16-3-1-2-14(11-16)10-13-4-6-15(7-5-13)30-20(27)28;/h1-9,11-12H,10H2,(H4,27,28,30)(H3,29,31,32);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019432
(CHEMBL3290698)Show SMILES Cl.CC(=O)Nc1cccc(Oc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H18ClF3N4O2.ClH/c1-13(31)28-15-3-2-4-18(11-15)32-17-8-5-14(6-9-17)29-21(27)30-16-7-10-20(23)19(12-16)22(24,25)26;/h2-12H,1H3,(H,28,31)(H3,27,29,30);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019447
(CHEMBL3290436)Show SMILES Cl.O=C(c1ccc(NC2=NCCN2)cc1)c1cccc(NC2=NCCN2)c1 |t:7,22| Show InChI InChI=1S/C19H20N6O.ClH/c26-17(13-4-6-15(7-5-13)24-18-20-8-9-21-18)14-2-1-3-16(12-14)25-19-22-10-11-23-19;/h1-7,12H,8-11H2,(H2,20,21,24)(H2,22,23,25);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019444
(CHEMBL3290433)Show InChI InChI=1S/C15H18N6.ClH/c16-14(17)20-12-6-4-10(5-7-12)8-11-2-1-3-13(9-11)21-15(18)19;/h1-7,9H,8H2,(H4,16,17,20)(H4,18,19,21);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019451
(CHEMBL3290688)Show SMILES Cl.NC(=N)Nc1cccc(Cc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C21H22N6.ClH/c22-20(23)25-19-8-4-5-16(14-19)13-15-9-11-18(12-10-15)27-21(24)26-17-6-2-1-3-7-17;/h1-12,14H,13H2,(H4,22,23,25)(H3,24,26,27);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019460
(CHEMBL3290695)Show SMILES Cl.NC(=N)Nc1cccc(Nc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C21H19ClF3N7.ClH/c22-18-9-8-16(11-17(18)21(23,24)25)32-20(28)31-13-6-4-12(5-7-13)29-14-2-1-3-15(10-14)30-19(26)27;/h1-11,29H,(H4,26,27,30)(H3,28,31,32);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019437
(CHEMBL3290430)Show InChI InChI=1S/C14H16N6O.ClH/c15-13(16)19-9-1-5-11(6-2-9)21-12-7-3-10(4-8-12)20-14(17)18;/h1-8H,(H4,15,16,19)(H4,17,18,20);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019448
(CHEMBL3290437)Show SMILES Cl.C(c1ccc(NC2=NCCN2)cc1)c1cccc(NC2=NCCN2)c1 |t:6,21| Show InChI InChI=1S/C19H22N6.ClH/c1-2-15(13-17(3-1)25-19-22-10-11-23-19)12-14-4-6-16(7-5-14)24-18-20-8-9-21-18;/h1-7,13H,8-12H2,(H2,20,21,24)(H2,22,23,25);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019460
(CHEMBL3290695)Show SMILES Cl.NC(=N)Nc1cccc(Nc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C21H19ClF3N7.ClH/c22-18-9-8-16(11-17(18)21(23,24)25)32-20(28)31-13-6-4-12(5-7-13)29-14-2-1-3-15(10-14)30-19(26)27;/h1-11,29H,(H4,26,27,30)(H3,28,31,32);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019447
(CHEMBL3290436)Show SMILES Cl.O=C(c1ccc(NC2=NCCN2)cc1)c1cccc(NC2=NCCN2)c1 |t:7,22| Show InChI InChI=1S/C19H20N6O.ClH/c26-17(13-4-6-15(7-5-13)24-18-20-8-9-21-18)14-2-1-3-16(12-14)25-19-22-10-11-23-19;/h1-7,12H,8-11H2,(H2,20,21,24)(H2,22,23,25);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019456
(CHEMBL3290693)Show SMILES Cl.NC(=N)Nc1cccc(c1)C(=O)c1ccc(NC(=N)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H18ClF3N6O.ClH/c23-18-9-8-16(11-17(18)22(24,25)26)32-21(29)31-14-6-4-12(5-7-14)19(33)13-2-1-3-15(10-13)30-20(27)28;/h1-11H,(H4,27,28,30)(H3,29,31,32);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019436
(CHEMBL3290699)Show SMILES Cl.CC(=O)Nc1cccc(Nc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H19ClF3N5O.ClH/c1-13(32)28-16-3-2-4-17(11-16)29-14-5-7-15(8-6-14)30-21(27)31-18-9-10-20(23)19(12-18)22(24,25)26;/h2-12,29H,1H3,(H,28,32)(H3,27,30,31);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019441
(CHEMBL3290431)Show InChI InChI=1S/C14H16N6O.ClH/c15-13(16)19-9-4-6-11(7-5-9)21-12-3-1-2-10(8-12)20-14(17)18;/h1-8H,(H4,15,16,19)(H4,17,18,20);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019442
(CHEMBL3290432)Show InChI InChI=1S/C15H16N6O.ClH/c16-14(17)20-11-6-4-9(5-7-11)13(22)10-2-1-3-12(8-10)21-15(18)19;/h1-8H,(H4,16,17,20)(H4,18,19,21);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019446
(CHEMBL3290435)Show SMILES Cl.C1CN=C(Nc2ccc(Oc3cccc(NC4=NCCN4)c3)cc2)N1 |t:2,16| Show InChI InChI=1S/C18H20N6O.ClH/c1-2-14(24-18-21-10-11-22-18)12-16(3-1)25-15-6-4-13(5-7-15)23-17-19-8-9-20-17;/h1-7,12H,8-11H2,(H2,19,20,23)(H2,21,22,24);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019456
(CHEMBL3290693)Show SMILES Cl.NC(=N)Nc1cccc(c1)C(=O)c1ccc(NC(=N)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H18ClF3N6O.ClH/c23-18-9-8-16(11-17(18)22(24,25)26)32-21(29)31-14-6-4-12(5-7-14)19(33)13-2-1-3-15(10-13)30-20(27)28;/h1-11H,(H4,27,28,30)(H3,29,31,32);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019428
(CHEMBL3290696)Show SMILES Cl.NC(=N)Nc1ccc(Oc2cccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)cc1 Show InChI InChI=1S/C21H18ClF3N6O.ClH/c22-18-9-6-14(11-17(18)21(23,24)25)31-20(28)30-13-2-1-3-16(10-13)32-15-7-4-12(5-8-15)29-19(26)27;/h1-11H,(H4,26,27,29)(H3,28,30,31);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019429
(CHEMBL3290697)Show SMILES Cl.NC(=N)Nc1ccc(Cc2cccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)cc1 Show InChI InChI=1S/C22H20ClF3N6.ClH/c23-19-9-8-17(12-18(19)22(24,25)26)32-21(29)31-16-3-1-2-14(11-16)10-13-4-6-15(7-5-13)30-20(27)28;/h1-9,11-12H,10H2,(H4,27,28,30)(H3,29,31,32);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019432
(CHEMBL3290698)Show SMILES Cl.CC(=O)Nc1cccc(Oc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H18ClF3N4O2.ClH/c1-13(31)28-15-3-2-4-18(11-15)32-17-8-5-14(6-9-17)29-21(27)30-16-7-10-20(23)19(12-16)22(24,25)26;/h2-12H,1H3,(H,28,31)(H3,27,29,30);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019450
(CHEMBL3290687)Show SMILES Cl.NC(=N)Nc1cccc(c1)C(=O)c1ccc(NC(=N)Nc2ccccc2)cc1 Show InChI InChI=1S/C21H20N6O.ClH/c22-20(23)25-18-8-4-5-15(13-18)19(28)14-9-11-17(12-10-14)27-21(24)26-16-6-2-1-3-7-16;/h1-13H,(H4,22,23,25)(H3,24,26,27);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019453
(CHEMBL3290690)Show SMILES Cl.NC(=N)Nc1ccc(Oc2cccc(NC(=N)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C20H20N6O.ClH/c21-19(22)24-15-9-11-17(12-10-15)27-18-8-4-7-16(13-18)26-20(23)25-14-5-2-1-3-6-14;/h1-13H,(H4,21,22,24)(H3,23,25,26);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019459
(CHEMBL3290694)Show SMILES Cl.NC(=N)Nc1cccc(Cc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C22H20ClF3N6.ClH/c23-19-9-8-17(12-18(19)22(24,25)26)32-21(29)31-15-6-4-13(5-7-15)10-14-2-1-3-16(11-14)30-20(27)28;/h1-9,11-12H,10H2,(H4,27,28,30)(H3,29,31,32);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019450
(CHEMBL3290687)Show SMILES Cl.NC(=N)Nc1cccc(c1)C(=O)c1ccc(NC(=N)Nc2ccccc2)cc1 Show InChI InChI=1S/C21H20N6O.ClH/c22-20(23)25-18-8-4-5-15(13-18)19(28)14-9-11-17(12-10-14)27-21(24)26-16-6-2-1-3-7-16;/h1-13H,(H4,22,23,25)(H3,24,26,27);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019445
(CHEMBL3290434)Show InChI InChI=1S/C14H17N7.ClH/c15-13(16)20-10-6-4-9(5-7-10)19-11-2-1-3-12(8-11)21-14(17)18;/h1-8,19H,(H4,15,16,20)(H4,17,18,21);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019448
(CHEMBL3290437)Show SMILES Cl.C(c1ccc(NC2=NCCN2)cc1)c1cccc(NC2=NCCN2)c1 |t:6,21| Show InChI InChI=1S/C19H22N6.ClH/c1-2-15(13-17(3-1)25-19-22-10-11-23-19)12-14-4-6-16(7-5-14)24-18-20-8-9-21-18;/h1-7,13H,8-12H2,(H2,20,21,24)(H2,22,23,25);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019455
(CHEMBL3290692)Show SMILES Cl.NC(=N)Nc1cccc(Oc2ccc(NC(=N)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C21H18ClF3N6O.ClH/c22-18-9-6-14(11-17(18)21(23,24)25)31-20(28)30-12-4-7-15(8-5-12)32-16-3-1-2-13(10-16)29-19(26)27;/h1-11H,(H4,26,27,29)(H3,28,30,31);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50019449
(CHEMBL3290438)Show SMILES Cl.NC(=N)Nc1cccc(Oc2ccc(NC(=N)Nc3ccccc3)cc2)c1 Show InChI InChI=1S/C20H20N6O.ClH/c21-19(22)24-16-7-4-8-18(13-16)27-17-11-9-15(10-12-17)26-20(23)25-14-5-2-1-3-6-14;/h1-13H,(H4,21,22,24)(H3,23,25,26);1H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GSK-3 beta after 30 mins by luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50019444
(CHEMBL3290433)Show InChI InChI=1S/C15H18N6.ClH/c16-14(17)20-12-6-4-10(5-7-12)8-11-2-1-3-13(9-11)21-15(18)19;/h1-7,9H,8H2,(H4,16,17,20)(H4,18,19,21);1H | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant casein kinase-1 delta using casein as substrate after 60 mins by kinase-glo luminescence assay |
Eur J Med Chem 81: 427-41 (2014)
Article DOI: 10.1016/j.ejmech.2014.05.025
BindingDB Entry DOI: 10.7270/Q2K075VT |
More data for this
Ligand-Target Pair | |
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