Found 22 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382388
(CHEMBL2023973)Show SMILES CC(=C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H20N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h9-11H,1,4-7H2,2-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319665
((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 12.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382382
(CHEMBL2023966)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 16.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382387
(CHEMBL2023972)Show SMILES CC(O)(O)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:17| Show InChI InChI=1S/C13H20N2O3S/c1-12(13(2,17)18)10(16)15-11(19-12)14-9-6-7-3-4-8(9)5-7/h7-9,17-18H,3-6H2,1-2H3,(H,14,15,16)/t7-,8+,9+,12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382383
(CHEMBL2023967)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11-,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382389
(CHEMBL2023968)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2CC3=O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H20N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-10H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382386
(CHEMBL2023971)Show SMILES C[C@]1(SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O)[C@H](O)CO |r,c:13| Show InChI InChI=1S/C13H20N2O3S/c1-13(10(17)6-16)11(18)15-12(19-13)14-9-5-7-2-3-8(9)4-7/h7-10,16-17H,2-6H2,1H3,(H,14,15,18)/t7-,8+,9+,10-,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382385
(CHEMBL2023970)Show SMILES C[C@]1(SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O)[C@@H](O)CO |r,c:13| Show InChI InChI=1S/C13H20N2O3S/c1-13(10(17)6-16)11(18)15-12(19-13)14-9-5-7-2-3-8(9)4-7/h7-10,16-17H,2-6H2,1H3,(H,14,15,18)/t7-,8+,9+,10+,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50319665
((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 70.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50382382
(CHEMBL2023966)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 152 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50382383
(CHEMBL2023967)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11-,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 181 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50382389
(CHEMBL2023968)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2CC3=O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H20N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-10H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382384
(CHEMBL2023969)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3C[C@@H](O)[C@H]2C3)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-8-4-9(10)11(17)6-8/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9+,10+,11-,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 449 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assay |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319665
((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382389
(CHEMBL2023968)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2CC3=O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H20N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-10H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382382
(CHEMBL2023966)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382383
(CHEMBL2023967)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@H]3C[C@@H]2C[C@H]3O)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-9-4-8(10)6-11(9)17/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9-,10+,11-,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382388
(CHEMBL2023973)Show SMILES CC(=C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H20N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h9-11H,1,4-7H2,2-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382387
(CHEMBL2023972)Show SMILES CC(O)(O)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:17| Show InChI InChI=1S/C13H20N2O3S/c1-12(13(2,17)18)10(16)15-11(19-12)14-9-6-7-3-4-8(9)5-7/h7-9,17-18H,3-6H2,1-2H3,(H,14,15,16)/t7-,8+,9+,12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382385
(CHEMBL2023970)Show SMILES C[C@]1(SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O)[C@@H](O)CO |r,c:13| Show InChI InChI=1S/C13H20N2O3S/c1-13(10(17)6-16)11(18)15-12(19-13)14-9-5-7-2-3-8(9)4-7/h7-10,16-17H,2-6H2,1H3,(H,14,15,18)/t7-,8+,9+,10+,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 71.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382386
(CHEMBL2023971)Show SMILES C[C@]1(SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O)[C@H](O)CO |r,c:13| Show InChI InChI=1S/C13H20N2O3S/c1-13(10(17)6-16)11(18)15-12(19-13)14-9-5-7-2-3-8(9)4-7/h7-10,16-17H,2-6H2,1H3,(H,14,15,18)/t7-,8+,9+,10-,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50382384
(CHEMBL2023969)Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3C[C@@H](O)[C@H]2C3)=NC1=O |r,c:17| Show InChI InChI=1S/C14H22N2O2S/c1-7(2)14(3)12(18)16-13(19-14)15-10-5-8-4-9(10)11(17)6-8/h7-11,17H,4-6H2,1-3H3,(H,15,16,18)/t8-,9+,10+,11-,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells |
ACS Med Chem Lett 2: 824-827 (2011)
Article DOI: 10.1021/ml2001467
BindingDB Entry DOI: 10.7270/Q22N539Z |
More data for this
Ligand-Target Pair | |
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