Affinity Data by PubMed id=24900272

PubMed code 24900272

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248926 (3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...) Show SMILES Clc1ccc(CN2CCC(Cn3c4ccccc4oc3=O)CC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50380360 (CHEMBL2017957) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295408 (3-[4-(N-Benzyl-N-methylamino)butyl]benzo[d]oxazol-...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248905 (3-((1-benzylpiperidin-4-yl)methyl)benzo[d]oxazol-2...) Show SMILES O=c1oc2ccccc2n1CC1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295411 (3-[4-[N-(4-Chlorobenzyl)-N-methylamino]butyl]benzo...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295422 (CHEMBL559979 \| N-Benzyl-1-(4-chlorobenzyl)piperidi...) Show SMILES Clc1ccc(CN2CCC(CC2)C(=O)NCc2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295421 (CHEMBL557297 \| N,1-Dibenzylpiperidine-4-carboxamid...) Show SMILES O=C(NCc1ccccc1)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50380361 (CHEMBL2017958) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295425 (3-[3-(N-Benzyl-N-methylamino)propyl]benzo[d]oxazol...) Show SMILES CN(CCCn1c2ccccc2oc1=O)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248959 (3-((1-(naphthalen-1-ylmethyl)piperidin-4-yl)methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295428 (3-[3-[N-(4-Chlorobenzyl)-N-methylamino]propyl]benz...) Show SMILES CN(CCCn1c2ccccc2oc1=O)Cc1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50380362 (CHEMBL2017959) Show SMILES CN(CC1CCN(CC1)C(=O)c1ccccc1)Cc1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%