Affinity Data by PubMed id=24949913

PubMed code 24949913

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 \| NSC_62969 \| VERAPAMIL) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 \| NSC_62969 \| VERAPAMIL) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 \| NSC_62969 \| VERAPAMIL) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mV				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 \| NSC_62969 \| VERAPAMIL) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mV				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%