Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50021357 (CHEMBL3288586) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 213 | n/a | n/a | n/a | n/a |
Ocean University of China Curated by ChEMBL | Assay Description Inhibition of p-glycoprotein in human MDA435/LCC6MDR cells assessed as concentration required to reduce taxol IC50 by half after 5 days by MTS assay | Eur J Med Chem 83: 74-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.016 BindingDB Entry DOI: 10.7270/Q2959K4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50021358 (CHEMBL3288595) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 211 | n/a | n/a | n/a | n/a |
Ocean University of China Curated by ChEMBL | Assay Description Inhibition of p-glycoprotein in human MDA435/LCC6MDR cells assessed as concentration required to reduce taxol IC50 by half after 5 days by MTS assay | Eur J Med Chem 83: 74-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.016 BindingDB Entry DOI: 10.7270/Q2959K4C | |||||||||||
More data for this Ligand-Target Pair |