Affinity Data by PubMed id=25016371

PubMed code 25016371

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049873 (CHEMBL3322287) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049868 (CHEMBL3322292) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049874 (CHEMBL3322286) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049872 (CHEMBL3322288) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049867 (CHEMBL3322293) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50038412 (2-Oxy-4-phenyl-furazan-3-carbonitrile \| 3-cyano-4-...) Show SMILES [O-][n+]1onc(c1C#N)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049864 (CHEMBL3322356) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049863 (CHEMBL3322357) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049871 (CHEMBL3322289) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049869 (CHEMBL3322291) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049870 (CHEMBL3322290) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049865 (CHEMBL3322355) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin glutathione reductase (Schistosoma mansoni)	BDBM50049866 (CHEMBL3322294) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ of Torino Curated by ChEMBL					Assay Description Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins				Eur J Med Chem 84: 135-45 (2014) Article DOI: 10.1016/j.ejmech.2014.07.007 BindingDB Entry DOI: 10.7270/Q21G0NW8
Universit£ of Torino Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%