Affinity Data by PubMed id=2522991

PubMed code 2522991

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016777 (((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...) Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011247 (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016771 (7-Diethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ...) Show SMILES CCN(CC)[C@@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016775 (7-Dibutylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ...) Show SMILES CCCCN(CCCC)[C@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016772 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CN(C)[C@@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016773 (7-Dibutylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ...) Show SMILES CCCCN(CCCC)[C@@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016776 (7-Diethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ...) Show SMILES CCN(CC)[C@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016770 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CN(C)[C@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	675	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluated				J Med Chem 32: 779-83 (1989) BindingDB Entry DOI: 10.7270/Q2736PW1
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%