Affinity Data by PubMed id=25314628

PubMed code 25314628

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030967 (CHEMBL1338624) Show SMILES NC1=NC2=C(CCCC2)C2(CCCCC2)S1 \|t:1,3\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030935 (CHEMBL3356577) Show SMILES COc1ccc2nc(NC(=O)C(C)C)sc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030937 (CHEMBL3356579) Show SMILES CC1(C)CNC(=O)c2sc(N)nc2C1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030941 (CHEMBL3356573) Show SMILES Nc1ccc2CCCN(C(=O)C3CC3)c2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030958 (CHEMBL3356575) Show SMILES Nc1cccc(c1)-c1nnc(o1)-c1cccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030938 (CHEMBL2335381) Show SMILES Cc1cc2n(C)c(=O)n(C)c2cc1N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030942 (CHEMBL3356574) Show SMILES Nc1cccc(c1)-c1n[nH]c(n1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030951 (CHEMBL389723) Show SMILES c1ccc(cc1)-c1nnc(o1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030940 (CHEMBL3356572) Show SMILES CCN1C(=O)CCc2cc(N)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030959 (CHEMBL3356576) Show SMILES Nc1ccccc1-c1nnc(o1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030936 (CHEMBL3356578) Show SMILES CC(C)(C)c1csc(NC(=O)C2CCC2)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50030939 (CHEMBL3356571) Show SMILES Cc1cc2ncccc2nc1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%