Affinity Data by PubMed id=25418070

PubMed code 25418070

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Caspase-1 (Homo sapiens (Human))	BDBM50033886 (CHEMBL2047937 \| Ethyl 2-((2-Chlorophenyl)(Hydroxy)...) Show SMILES CCOC(=O)C(=C)C(O)c1ccccc1Cl Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of caspase 1 (unknown origin) using N-acetyl-Tyr-Val-Ala-Asp-para-nitroanilide substrate assessed as rate of para-nitroanilide release by ...				J Med Chem 57: 10366-82 (2014) Article DOI: 10.1021/jm501072b BindingDB Entry DOI: 10.7270/Q29P337T
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Caspase-1 (Homo sapiens (Human))	BDBM50433441 (PARTHENOLIDE) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of caspase 1 (unknown origin) using N-acetyl-Tyr-Val-Ala-Asp-para-nitroanilide substrate assessed as rate of para-nitroanilide release by ...				J Med Chem 57: 10366-82 (2014) Article DOI: 10.1021/jm501072b BindingDB Entry DOI: 10.7270/Q29P337T
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%