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PubMed code 25462626

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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KEGG
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PDB
UniChem

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Article
PubMed
n/an/a 3.83E+4n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67524
PNG
(6-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-1-c...)
Show SMILES Oc1ccccc1-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H16N2O/c24-18-14-8-7-13-17(18)21-22-19(15-9-3-1-4-10-15)20(23-21)16-11-5-2-6-12-16/h1-14,24H,(H,22,23)
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PubMed
n/an/a 7.43E+4n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67466
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-1-c...)
Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H16N2O/c24-18-13-11-17(12-14-18)21-22-19(15-7-3-1-4-8-15)20(23-21)16-9-5-2-6-10-16/h1-14,24H,(H,22,23)
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n/an/a 9.71E+4n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM150749
PNG
(2-(4,5-Diphenyl-1H-imidazol-2-yl)-6-methoxyphenol ...)
Show SMILES COc1cccc(-c2nc(c([nH]2)-c2ccccc2)-c2ccccc2)c1O
Show InChI InChI=1S/C22H18N2O2/c1-26-18-14-8-13-17(21(18)25)22-23-19(15-9-4-2-5-10-15)20(24-22)16-11-6-3-7-12-16/h2-14,25H,1H3,(H,23,24)
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n/an/a 1.07E+5n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67462
PNG
(2-(3-methoxyphenyl)-4,5-diphenyl-1H-imidazole | SR...)
Show SMILES COc1cccc(c1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O/c1-25-19-14-8-13-18(15-19)22-23-20(16-9-4-2-5-10-16)21(24-22)17-11-6-3-7-12-17/h2-15H,1H3,(H,23,24)
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PubMed
n/an/a 3.59E+5n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
Oligo-1,6-glucosidase IMA1


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67523
PNG
(2-(4-chlorophenyl)-4,5-diphenyl-1H-imidazole | SR-...)
Show SMILES Clc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15ClN2/c22-18-13-11-17(12-14-18)21-23-19(15-7-3-1-4-8-15)20(24-21)16-9-5-2-6-10-16/h1-14H,(H,23,24)
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PubMed
n/an/a 4.58E+5n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)


Article DOI: 10.1016/j.bioorg.2014.11.006
BindingDB Entry DOI: 10.7270/Q22N5103
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%