Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain (Bos taurus) | BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of bovine brain tubulin polymerization | Bioorg Med Chem Lett 25: 631-4 (2015) Article DOI: 10.1016/j.bmcl.2014.12.004 BindingDB Entry DOI: 10.7270/Q2DN46PV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50042033 (CHEMBL3360145) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of bovine brain tubulin polymerization | Bioorg Med Chem Lett 25: 631-4 (2015) Article DOI: 10.1016/j.bmcl.2014.12.004 BindingDB Entry DOI: 10.7270/Q2DN46PV | |||||||||||
More data for this Ligand-Target Pair |