Affinity Data by PubMed id=25559742

PubMed code 25559742

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50062617 (CHEMBL3397685) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using chromogenic substrate S-2765 preincubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50062618 (CHEMBL3397706) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using chromogenic substrate S-2765 preincubated for 10 mins by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50062618 (CHEMBL3397706) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of trypsin (unknown origin) using chromogenic substrate S-2222 by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50062618 (CHEMBL3397706) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin) using chromogenic substrate S-2238 by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50062617 (CHEMBL3397685) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin) using chromogenic substrate S-2238 by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50062617 (CHEMBL3397685) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of trypsin (unknown origin) using chromogenic substrate S-2222 by spectrophotometry				Bioorg Med Chem Lett 25: 492-5 (2015) Article DOI: 10.1016/j.bmcl.2014.12.039 BindingDB Entry DOI: 10.7270/Q2611201
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%