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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM150754 (11-O-acetyl-aloe-emodin | 3-[(acetyloxy)methyl]-1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | 7.5 | 30 |
Université Pierre et Marie Curie | Assay Description We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris¿¿HCl (25 mm, pH 7.5), MgCl2 (10 mm... | Chembiochem 16: 432-9 (2015) Article DOI: 10.1002/cbic.201402579 BindingDB Entry DOI: 10.7270/Q2T43RTF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM150752 (4-hydrazino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.83E+4 | n/a | n/a | n/a | 7.5 | 30 |
Université Pierre et Marie Curie | Assay Description We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris¿¿HCl (25 mm, pH 7.5), MgCl2 (10 mm... | Chembiochem 16: 432-9 (2015) Article DOI: 10.1002/cbic.201402579 BindingDB Entry DOI: 10.7270/Q2T43RTF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM43654 (7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.87E+5 | n/a | n/a | n/a | 7.5 | 30 |
Université Pierre et Marie Curie | Assay Description We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris¿¿HCl (25 mm, pH 7.5), MgCl2 (10 mm... | Chembiochem 16: 432-9 (2015) Article DOI: 10.1002/cbic.201402579 BindingDB Entry DOI: 10.7270/Q2T43RTF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM32021 (4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | 7.5 | 30 |
Université Pierre et Marie Curie | Assay Description We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris¿¿HCl (25 mm, pH 7.5), MgCl2 (10 mm... | Chembiochem 16: 432-9 (2015) Article DOI: 10.1002/cbic.201402579 BindingDB Entry DOI: 10.7270/Q2T43RTF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM150753 (4-hydrazino-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.25E+4 | n/a | n/a | n/a | 7.5 | 30 |
Université Pierre et Marie Curie | Assay Description We incubated human recombinant CDK2/cyclin A with small molecules at the indicatedconcentrations in buffer A (Tris¿¿HCl (25 mm, pH 7.5), MgCl2 (10 mm... | Chembiochem 16: 432-9 (2015) Article DOI: 10.1002/cbic.201402579 BindingDB Entry DOI: 10.7270/Q2T43RTF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
