Found 73 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078191
(CHEMBL3417750)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)F)cc2)cc1 Show InChI InChI=1S/C23H26F2N2O6S/c24-21(25)33-18-3-1-16(2-4-18)32-17-5-7-19(8-6-17)34(30,31)23(20(28)27-29)10-9-22(15-23)11-13-26-14-12-22/h1-8,21,26,29H,9-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078196
(CHEMBL3417745)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O6S/c24-23(25,26)34-18-3-1-16(2-4-18)33-17-5-7-19(8-6-17)35(31,32)22(20(29)28-30)10-9-21(15-22)11-13-27-14-12-21/h1-8,27,30H,9-15H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078191
(CHEMBL3417750)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)F)cc2)cc1 Show InChI InChI=1S/C23H26F2N2O6S/c24-21(25)33-18-3-1-16(2-4-18)32-17-5-7-19(8-6-17)34(30,31)23(20(28)27-29)10-9-22(15-23)11-13-26-14-12-22/h1-8,21,26,29H,9-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078196
(CHEMBL3417745)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O6S/c24-23(25,26)34-18-3-1-16(2-4-18)33-17-5-7-19(8-6-17)35(31,32)22(20(29)28-30)10-9-21(15-22)11-13-27-14-12-21/h1-8,27,30H,9-15H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078175
(CHEMBL3417766)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CC3)C(C)=O)C(=O)NO)cc1 Show InChI InChI=1S/C25H30N2O7S/c1-18(28)27-15-13-24(14-16-27)11-12-25(17-24,23(29)26-30)35(31,32)22-9-7-21(8-10-22)34-20-5-3-19(33-2)4-6-20/h3-10,30H,11-17H2,1-2H3,(H,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078176
(CHEMBL3417765)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CCC(F)(F)F)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H31F3N2O6S/c1-36-19-2-4-20(5-3-19)37-21-6-8-22(9-7-21)38(34,35)25(23(32)30-33)11-10-24(18-25)12-15-31(16-13-24)17-14-26(27,28)29/h2-9,33H,10-18H2,1H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078193
(CHEMBL3417748)Show SMILES Cc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O5S/c1-17-2-4-18(5-3-17)30-19-6-8-20(9-7-19)31(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078193
(CHEMBL3417748)Show SMILES Cc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O5S/c1-17-2-4-18(5-3-17)30-19-6-8-20(9-7-19)31(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078186
(CHEMBL3417755)Show SMILES COc1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C23H28N2O6S/c1-30-18-3-2-4-19(15-18)31-17-5-7-20(8-6-17)32(28,29)23(21(26)25-27)10-9-22(16-23)11-13-24-14-12-22/h2-8,15,24,27H,9-14,16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078199
(CHEMBL3417742)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-2-4-18(5-3-17)31-19-6-8-20(9-7-19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078175
(CHEMBL3417766)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CC3)C(C)=O)C(=O)NO)cc1 Show InChI InChI=1S/C25H30N2O7S/c1-18(28)27-15-13-24(14-16-27)11-12-25(17-24,23(29)26-30)35(31,32)22-9-7-21(8-10-22)34-20-5-3-19(33-2)4-6-20/h3-10,30H,11-17H2,1-2H3,(H,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078177
(CHEMBL3417764)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(C)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H30N2O6S/c1-26-15-13-23(14-16-26)11-12-24(17-23,22(27)25-28)33(29,30)21-9-7-20(8-10-21)32-19-5-3-18(31-2)4-6-19/h3-10,28H,11-17H2,1-2H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078199
(CHEMBL3417742)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-2-4-18(5-3-17)31-19-6-8-20(9-7-19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078171
(CHEMBL3417770)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078189
(CHEMBL3417752)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(cc2)C(=O)N2CCCC2)cc1 Show InChI InChI=1S/C27H33N3O6S/c31-24(30-17-1-2-18-30)20-3-5-21(6-4-20)36-22-7-9-23(10-8-22)37(34,35)27(25(32)29-33)12-11-26(19-27)13-15-28-16-14-26/h3-10,28,33H,1-2,11-19H2,(H,29,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078186
(CHEMBL3417755)Show SMILES COc1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C23H28N2O6S/c1-30-18-3-2-4-19(15-18)31-17-5-7-20(8-6-17)32(28,29)23(21(26)25-27)10-9-22(16-23)11-13-24-14-12-22/h2-8,15,24,27H,9-14,16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078171
(CHEMBL3417770)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078174
(CHEMBL3417767)Show SMILES COc1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H28N2O7S/c1-32-18-4-2-17(3-5-18)21(27)33-19-6-8-20(9-7-19)34(30,31)24(22(28)26-29)11-10-23(16-24)12-14-25-15-13-23/h2-9,25,29H,10-16H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078187
(CHEMBL3417754)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cn1 Show InChI InChI=1S/C22H27N3O6S/c1-30-19-7-4-17(14-24-19)31-16-2-5-18(6-3-16)32(28,29)22(20(26)25-27)9-8-21(15-22)10-12-23-13-11-21/h2-7,14,23,27H,8-13,15H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078176
(CHEMBL3417765)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CCC(F)(F)F)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H31F3N2O6S/c1-36-19-2-4-20(5-3-19)37-21-6-8-22(9-7-21)38(34,35)25(23(32)30-33)11-10-24(18-25)12-15-31(16-13-24)17-14-26(27,28)29/h2-9,33H,10-18H2,1H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078177
(CHEMBL3417764)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(C)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H30N2O6S/c1-26-15-13-23(14-16-26)11-12-24(17-23,22(27)25-28)33(29,30)21-9-7-20(8-10-21)32-19-5-3-18(31-2)4-6-19/h3-10,28H,11-17H2,1-2H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078172
(CHEMBL3417769)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078174
(CHEMBL3417767)Show SMILES COc1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H28N2O7S/c1-32-18-4-2-17(3-5-18)21(27)33-19-6-8-20(9-7-19)34(30,31)24(22(28)26-29)11-10-23(16-24)12-14-25-15-13-23/h2-9,25,29H,10-16H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078172
(CHEMBL3417769)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078189
(CHEMBL3417752)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(cc2)C(=O)N2CCCC2)cc1 Show InChI InChI=1S/C27H33N3O6S/c31-24(30-17-1-2-18-30)20-3-5-21(6-4-20)36-22-7-9-23(10-8-22)37(34,35)27(25(32)29-33)12-11-26(19-27)13-15-28-16-14-26/h3-10,28,33H,1-2,11-19H2,(H,29,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078195
(CHEMBL3417746)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H27F3N2O6S/c25-24(26,27)35-19-3-1-17(2-4-19)15-34-18-5-7-20(8-6-18)36(32,33)23(21(30)29-31)10-9-22(16-23)11-13-28-14-12-22/h1-8,28,31H,9-16H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078190
(CHEMBL3417751)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078190
(CHEMBL3417751)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078192
(CHEMBL3417749)Show SMILES CC(C)(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H34N2O5S/c1-24(2,3)19-4-6-20(7-5-19)33-21-8-10-22(11-9-21)34(31,32)26(23(29)28-30)13-12-25(18-26)14-16-27-17-15-25/h4-11,27,30H,12-18H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078195
(CHEMBL3417746)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H27F3N2O6S/c25-24(26,27)35-19-3-1-17(2-4-19)15-34-18-5-7-20(8-6-18)36(32,33)23(21(30)29-31)10-9-22(16-23)11-13-28-14-12-22/h1-8,28,31H,9-16H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078180
(CHEMBL3417761)Show SMILES CNC(=O)c1ccc(COc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H31N3O6S/c1-26-22(29)19-4-2-18(3-5-19)16-34-20-6-8-21(9-7-20)35(32,33)25(23(30)28-31)11-10-24(17-25)12-14-27-15-13-24/h2-9,27,31H,10-17H2,1H3,(H,26,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078192
(CHEMBL3417749)Show SMILES CC(C)(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H34N2O5S/c1-24(2,3)19-4-6-20(7-5-19)33-21-8-10-22(11-9-21)34(31,32)26(23(29)28-30)13-12-25(18-26)14-16-27-17-15-25/h4-11,27,30H,12-18H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078181
(CHEMBL3417760)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H28N2O5S/c26-21(25-27)23(11-10-22(17-23)12-14-24-15-13-22)31(28,29)20-8-6-19(7-9-20)30-16-18-4-2-1-3-5-18/h1-9,24,27H,10-17H2,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078181
(CHEMBL3417760)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H28N2O5S/c26-21(25-27)23(11-10-22(17-23)12-14-24-15-13-22)31(28,29)20-8-6-19(7-9-20)30-16-18-4-2-1-3-5-18/h1-9,24,27H,10-17H2,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078187
(CHEMBL3417754)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cn1 Show InChI InChI=1S/C22H27N3O6S/c1-30-19-7-4-17(14-24-19)31-16-2-5-18(6-3-16)32(28,29)22(20(26)25-27)9-8-21(15-22)10-12-23-13-11-21/h2-7,14,23,27H,8-13,15H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078184
(CHEMBL3417757)Show SMILES CNC(=O)c1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-3-2-4-19(15-17)33-18-5-7-20(8-6-18)34(31,32)24(22(29)27-30)10-9-23(16-24)11-13-26-14-12-23/h2-8,15,26,30H,9-14,16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078180
(CHEMBL3417761)Show SMILES CNC(=O)c1ccc(COc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H31N3O6S/c1-26-22(29)19-4-2-18(3-5-19)16-34-20-6-8-21(9-7-20)35(32,33)25(23(30)28-31)11-10-24(17-25)12-14-27-15-13-24/h2-9,27,31H,10-17H2,1H3,(H,26,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078200
(CHEMBL3417741)Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C17H24N2O5S/c1-24-13-2-4-14(5-3-13)25(22,23)17(15(20)19-21)7-6-16(12-17)8-10-18-11-9-16/h2-5,18,21H,6-12H2,1H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078184
(CHEMBL3417757)Show SMILES CNC(=O)c1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-3-2-4-19(15-17)33-18-5-7-20(8-6-18)34(31,32)24(22(29)27-30)10-9-23(16-24)11-13-26-14-12-23/h2-8,15,26,30H,9-14,16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078200
(CHEMBL3417741)Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C17H24N2O5S/c1-24-13-2-4-14(5-3-13)25(22,23)17(15(20)19-21)7-6-16(12-17)8-10-18-11-9-16/h2-5,18,21H,6-12H2,1H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078173
(CHEMBL3417768)Show SMILES CNC(=O)c1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C25H29N3O7S/c1-26-21(29)17-2-4-18(5-3-17)22(30)35-19-6-8-20(9-7-19)36(33,34)25(23(31)28-32)11-10-24(16-25)12-14-27-15-13-24/h2-9,27,32H,10-16H2,1H3,(H,26,29)(H,28,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078194
(CHEMBL3417747)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(NCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H28F3N3O5S/c25-24(26,27)35-19-5-1-17(2-6-19)15-29-18-3-7-20(8-4-18)36(33,34)23(21(31)30-32)10-9-22(16-23)11-13-28-14-12-22/h1-8,28-29,32H,9-16H2,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078173
(CHEMBL3417768)Show SMILES CNC(=O)c1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C25H29N3O7S/c1-26-21(29)17-2-4-18(5-3-17)22(30)35-19-6-8-20(9-7-19)36(33,34)25(23(31)28-32)11-10-24(16-25)12-14-27-15-13-24/h2-9,27,32H,10-16H2,1H3,(H,26,29)(H,28,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078198
(CHEMBL3417743)Show SMILES COc1ccc(Oc2cccc(c2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-5-7-18(8-6-17)31-19-3-2-4-20(15-19)32(28,29)23(21(26)25-27)10-9-22(16-23)11-13-24-14-12-22/h2-8,15,24,27H,9-14,16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078194
(CHEMBL3417747)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(NCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H28F3N3O5S/c25-24(26,27)35-19-5-1-17(2-6-19)15-29-18-3-7-20(8-4-18)36(33,34)23(21(31)30-32)10-9-22(16-23)11-13-28-14-12-22/h1-8,28-29,32H,9-16H2,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078198
(CHEMBL3417743)Show SMILES COc1ccc(Oc2cccc(c2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-5-7-18(8-6-17)31-19-3-2-4-20(15-19)32(28,29)23(21(26)25-27)10-9-22(16-23)11-13-24-14-12-22/h2-8,15,24,27H,9-14,16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078182
(CHEMBL3417759)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1OC Show InChI InChI=1S/C25H31N3O7S/c1-26-22(29)20-8-5-18(15-21(20)34-2)35-17-3-6-19(7-4-17)36(32,33)25(23(30)28-31)10-9-24(16-25)11-13-27-14-12-24/h3-8,15,27,31H,9-14,16H2,1-2H3,(H,26,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078179
(CHEMBL3417762)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCCN2CCCC2=O)cc1 Show InChI InChI=1S/C22H31N3O6S/c26-19-2-1-13-25(19)14-15-31-17-3-5-18(6-4-17)32(29,30)22(20(27)24-28)8-7-21(16-22)9-11-23-12-10-21/h3-6,23,28H,1-2,7-16H2,(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 435 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078179
(CHEMBL3417762)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCCN2CCCC2=O)cc1 Show InChI InChI=1S/C22H31N3O6S/c26-19-2-1-13-25(19)14-15-31-17-3-5-18(6-4-17)32(29,30)22(20(27)24-28)8-7-21(16-22)9-11-23-12-10-21/h3-6,23,28H,1-2,7-16H2,(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 476 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078182
(CHEMBL3417759)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1OC Show InChI InChI=1S/C25H31N3O7S/c1-26-22(29)20-8-5-18(15-21(20)34-2)35-17-3-6-19(7-4-17)36(32,33)25(23(30)28-31)10-9-24(16-25)11-13-27-14-12-24/h3-8,15,27,31H,9-14,16H2,1-2H3,(H,26,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 713 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078185
(CHEMBL3417756)Show SMILES COc1ccccc1Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C23H28N2O6S/c1-30-19-4-2-3-5-20(19)31-17-6-8-18(9-7-17)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 739 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078185
(CHEMBL3417756)Show SMILES COc1ccccc1Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C23H28N2O6S/c1-30-19-4-2-3-5-20(19)31-17-6-8-18(9-7-17)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 916 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078188
(CHEMBL3417753)Show SMILES CN(C)Cc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H33N3O5S/c1-28(2)17-19-3-5-20(6-4-19)33-21-7-9-22(10-8-21)34(31,32)25(23(29)27-30)12-11-24(18-25)13-15-26-16-14-24/h3-10,26,30H,11-18H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078188
(CHEMBL3417753)Show SMILES CN(C)Cc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H33N3O5S/c1-28(2)17-19-3-5-20(6-4-19)33-21-7-9-22(10-8-21)34(31,32)25(23(29)27-30)12-11-24(18-25)13-15-26-16-14-24/h3-10,26,30H,11-18H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078178
(CHEMBL3417763)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)c(Cl)c1 Show InChI InChI=1S/C23H24ClF3N2O6S/c24-18-13-17(5-6-19(18)34-15-1-3-16(4-2-15)35-23(25,26)27)36(32,33)22(20(30)29-31)8-7-21(14-22)9-11-28-12-10-21/h1-6,13,28,31H,7-12,14H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078178
(CHEMBL3417763)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)c(Cl)c1 Show InChI InChI=1S/C23H24ClF3N2O6S/c24-18-13-17(5-6-19(18)34-15-1-3-16(4-2-15)35-23(25,26)27)36(32,33)22(20(30)29-31)8-7-21(14-22)9-11-28-12-10-21/h1-6,13,28,31H,7-12,14H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078170
(CHEMBL3417740)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H21FN2O4S/c17-12-1-3-13(4-2-12)24(22,23)16(14(20)19-21)6-5-15(11-16)7-9-18-10-8-15/h1-4,18,21H,5-11H2,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078170
(CHEMBL3417740)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H21FN2O4S/c17-12-1-3-13(4-2-12)24(22,23)16(14(20)19-21)6-5-15(11-16)7-9-18-10-8-15/h1-4,18,21H,5-11H2,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078197
(CHEMBL3417744)Show SMILES COc1ccc(Oc2ccccc2S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-6-8-18(9-7-17)31-19-4-2-3-5-20(19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078183
(CHEMBL3417758)Show SMILES CNC(=O)c1ccccc1Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)19-4-2-3-5-20(19)33-17-6-8-18(9-7-17)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50078197
(CHEMBL3417744)Show SMILES COc1ccc(Oc2ccccc2S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-6-8-18(9-7-17)31-19-4-2-3-5-20(19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078171
(CHEMBL3417770)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel by patch clamp technique |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078172
(CHEMBL3417769)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel by patch clamp technique |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078199
(CHEMBL3417742)Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-2-4-18(5-3-17)31-19-6-8-20(9-7-19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50078183
(CHEMBL3417758)Show SMILES CNC(=O)c1ccccc1Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)19-4-2-3-5-20(19)33-17-6-8-18(9-7-17)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3 (unknown origin) measured every minute for 1 hr by fluorescence assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078195
(CHEMBL3417746)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H27F3N2O6S/c25-24(26,27)35-19-3-1-17(2-4-19)15-34-18-5-7-20(8-6-18)36(32,33)23(21(30)29-31)10-9-22(16-23)11-13-28-14-12-22/h1-8,28,31H,9-16H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078174
(CHEMBL3417767)Show SMILES COc1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H28N2O7S/c1-32-18-4-2-17(3-5-18)21(27)33-19-6-8-20(9-7-19)34(30,31)24(22(28)26-29)11-10-23(16-24)12-14-25-15-13-23/h2-9,25,29H,10-16H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078172
(CHEMBL3417769)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078189
(CHEMBL3417752)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(cc2)C(=O)N2CCCC2)cc1 Show InChI InChI=1S/C27H33N3O6S/c31-24(30-17-1-2-18-30)20-3-5-21(6-4-20)36-22-7-9-23(10-8-22)37(34,35)27(25(32)29-33)12-11-26(19-27)13-15-28-16-14-26/h3-10,28,33H,1-2,11-19H2,(H,29,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078180
(CHEMBL3417761)Show SMILES CNC(=O)c1ccc(COc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H31N3O6S/c1-26-22(29)19-4-2-18(3-5-19)16-34-20-6-8-21(9-7-20)35(32,33)25(23(30)28-31)11-10-24(17-25)12-14-27-15-13-24/h2-9,27,31H,10-17H2,1H3,(H,26,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078196
(CHEMBL3417745)Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O6S/c24-23(25,26)34-18-3-1-16(2-4-18)33-17-5-7-19(8-6-17)35(31,32)22(20(29)28-30)10-9-21(15-22)11-13-27-14-12-21/h1-8,27,30H,9-15H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078190
(CHEMBL3417751)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50078171
(CHEMBL3417770)Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra
Curated by ChEMBL
| Assay Description
Inhibition of human ERG channel after 2 hrs by fluorescence polarization assay |
J Med Chem 58: 2465-88 (2015)
Article DOI: 10.1021/jm501940y
BindingDB Entry DOI: 10.7270/Q28C9XXK |
More data for this
Ligand-Target Pair | |
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