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PubMed code 25719566

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain adjacent to zinc finger domain protein 2A


(Homo sapiens (Human))
BDBM50078630
PNG
(CHEMBL4296718)
Show SMILES Cn1cc(CCn2cnc(-c3cnn(C)c3)c2-c2ccc(cc2)C#N)cn1
Show InChI InChI=1S/C20H17N7/c1-15-13-27(25-24-15)10-9-26-14-23-19(18-3-2-8-22-12-18)20(26)17-6-4-16(11-21)5-7-17/h2-8,12-14H,9-10H2,1H3
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 136n/an/an/an/an/an/a



Cancer Research UK Cancer Therapeutics Unit

Curated by ChEMBL


Assay Description
Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...


J Med Chem 58: 2553-9 (2015)


Article DOI: 10.1021/jm501963e
BindingDB Entry DOI: 10.7270/Q2862M28
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Bromodomain adjacent to zinc finger domain protein 2B


(Homo sapiens (Human))
BDBM50078630
PNG
(CHEMBL4296718)
Show SMILES Cn1cc(CCn2cnc(-c3cnn(C)c3)c2-c2ccc(cc2)C#N)cn1
Show InChI InChI=1S/C20H17N7/c1-15-13-27(25-24-15)10-9-26-14-23-19(18-3-2-8-22-12-18)20(26)17-6-4-16(11-21)5-7-17/h2-8,12-14H,9-10H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 174n/an/an/an/an/an/a



Cancer Research UK Cancer Therapeutics Unit

Curated by ChEMBL


Assay Description
Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...


J Med Chem 58: 2553-9 (2015)


Article DOI: 10.1021/jm501963e
BindingDB Entry DOI: 10.7270/Q2862M28
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%