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PubMed code 25768699

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 1


(Homo sapiens (Human))
BDBM50078891
PNG
(CHEMBL1973716)
Show SMILES Brc1ccc2n(CC(=O)NNC(=S)NC3CCCCC3)c3nc4ccccc4nc3c2c1
Show InChI InChI=1S/C23H23BrN6OS/c24-14-10-11-19-16(12-14)21-22(27-18-9-5-4-8-17(18)26-21)30(19)13-20(31)28-29-23(32)25-15-6-2-1-3-7-15/h4-5,8-12,15H,1-3,6-7,13H2,(H,28,31)(H2,25,29,32)
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Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



Universit£ degli Studi di Palermo

Curated by ChEMBL


Assay Description
Inhibition of CDC2 kinase (unknown origin) using histone H1 and [32P]-ATP


Eur J Med Chem 94: 149-62 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.005
BindingDB Entry DOI: 10.7270/Q2PG1TFS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%