Affinity Data by PubMed id=25768707

PubMed code 25768707

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50376383 (CHEMBL259972) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084631 (CHEMBL3427203) Show SMILES COc1nc(-c2ccc(OC)cc2)n(n1)-c1ccc(OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM13065 (5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50376383 (CHEMBL259972) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) Show SMILES Cc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084649 (CHEMBL3114664) Show SMILES Nc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084642 (CHEMBL3427198) Show SMILES COc1ccc(cc1)-n1nnc(c1C)-c1ccc(N)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084631 (CHEMBL3427203) Show SMILES COc1nc(-c2ccc(OC)cc2)n(n1)-c1ccc(OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of LPS-induced COX2 in human whole blood assessed as reduction in PGH2 levels by radioimmunoassay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084632 (CHEMBL3427204) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccco1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084645 (CHEMBL3114671) Show SMILES Cc1onc(-c2ccc(Cl)o2)c1-c1ccc(N)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084643 (CHEMBL3427197) Show SMILES Cc1c(nnn1-c1ccc(N)cc1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084639 (CHEMBL3427202) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084644 (CHEMBL3114659) Show SMILES COc1ccccc1-c1noc(C)c1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50084647 (CHEMBL3114661) Show SMILES CCc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) Show SMILES Cc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM13065 (5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) Show SMILES Cc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					Assay Description Inhibition of LPS-induced COX2 in human whole blood assessed as reduction in PGH2 levels by radioimmunoassay				Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%