Affinity Data by PubMed id=25874336

PubMed code 25874336

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079877 (CHEMBL3415025) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1ccc(Cl)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079876 (CHEMBL3415024) Show SMILES Cc1ccc(cc1)-c1nc2c(nc(C)[nH]c2=O)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079875 (CHEMBL3415023) Show SMILES COc1ccc(cc1)-c1nc2c(nc(C)[nH]c2=O)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079874 (CHEMBL3415022) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079878 (CHEMBL3415026) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1ccc(F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079883 (CHEMBL3415033) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1cccc(F)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079801 (CHEMBL3415054) Show SMILES CCOc1nc(C)nc2sc(Nc3cccc(OC)c3)nc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079888 (CHEMBL3415046) Show SMILES COc1cccc(Nc2nc3c(nc(C)[nH]c3=O)s2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079887 (CHEMBL3415040) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-n1cccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	227	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079886 (CHEMBL3415039) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079879 (CHEMBL3415031) Show SMILES Cc1cccc(c1)-c1nc2c(nc(C)[nH]c2=O)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	384	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079885 (CHEMBL3415035) Show SMILES Cc1nc2sc(Cc3ccccc3)nc2c(=O)[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079796 (CHEMBL3415047) Show SMILES Cc1cccc(Nc2nc3c(nc(C)[nH]c3=O)s2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079880 (CHEMBL3415032) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	826	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079877 (CHEMBL3415025) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1ccc(Cl)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Antagonist activity against human adenosine A3 receptor expressed in CHO cells assessed as blockade of Cl-IB-MECA-induced inhibition of forskolin-ind...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50079874 (CHEMBL3415022) Show SMILES Cc1nc2sc(nc2c(=O)[nH]1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Antagonist activity against human adenosine A3 receptor expressed in CHO cells assessed as blockade of Cl-IB-MECA-induced inhibition of forskolin-ind...				Eur J Med Chem 96: 105-21 (2015) Article DOI: 10.1016/j.ejmech.2015.04.010 BindingDB Entry DOI: 10.7270/Q2V126HP
Universita' di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%