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PubMed code 26035635

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50000788
PNG
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r|
Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
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Article
PubMed
30n/an/an/an/an/an/an/an/a



University of Mississippi

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) transfected into HEK293 cells by microplate scintillation counting


J Nat Prod 78: 1461-5 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00218
BindingDB Entry DOI: 10.7270/Q27P915R
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50092614
PNG
(5-demethylsinensetin | CHEMBL226508)
Show SMILES COc1ccc(cc1OC)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C19H18O7/c1-22-12-6-5-10(7-14(12)23-2)13-8-11(20)17-15(26-13)9-16(24-3)19(25-4)18(17)21/h5-9,21H,1-4H3
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Article
PubMed
3.10E+3n/an/an/an/an/an/an/an/a



University of Mississippi

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) transfected into HEK293 cells by microplate scintillation counting


J Nat Prod 78: 1461-5 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00218
BindingDB Entry DOI: 10.7270/Q27P915R
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50064896
PNG
(4,5-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chrom...)
Show SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(O)cc2o1
Show InChI InChI=1S/C17H14O6/c1-21-10-5-3-9(4-6-10)13-7-11(18)15-14(23-13)8-12(19)17(22-2)16(15)20/h3-8,19-20H,1-2H3
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Article
PubMed
8.40E+3n/an/an/an/an/an/an/an/a



University of Mississippi

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) transfected into HEK293 cells by microplate scintillation counting


J Nat Prod 78: 1461-5 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00218
BindingDB Entry DOI: 10.7270/Q27P915R
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50092613
PNG
(Salvigenin)
Show SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C18H16O6/c1-21-11-6-4-10(5-7-11)13-8-12(19)16-14(24-13)9-15(22-2)18(23-3)17(16)20/h4-9,20H,1-3H3
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Article
PubMed
>2.60E+4n/an/an/an/an/an/an/an/a



University of Mississippi

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) transfected into HEK293 cells by microplate scintillation counting


J Nat Prod 78: 1461-5 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00218
BindingDB Entry DOI: 10.7270/Q27P915R
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%