Affinity Data by PubMed id=26057861

PubMed code 26057861

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152554 (7,8-dimethoxy-5-((1-(4-nitrophenylsulfonyl)piperid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152555 (7,8-dimethoxy-5-((1-(methylsulfonyl)piperidin-4-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152556 (7,8-dimethoxy-5-((1-(4-(trifluoromethyl)phenylsulf...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152557 (7,8-dimethoxy-5-((1-(2-nitrophenylsulfonyl)piperid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152560 (7,8-dimethoxy-5-((1-(thiophen-2-ylsulfonyl)piperid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50300205 (7,8-Dimethoxy-5-methyl-1H-benzo[e]isoindole-1,3(2H...) Show SMILES COc1cc2c3C(=O)NC(=O)c3cc(C)c2cc1OC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152558 (7,8-dimethoxy-5-((1-(phenylsulfonyl)piperidin-4-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152559 (7,8-dimethoxy-5-((1-(quinolin-8-ylsulfonyl)piperid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152553 (7,8-dimethoxy-5-((1-(4-methoxyphenylsulfonyl)piper...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM152552 (7,8-dimethoxy-5-({[1-(4-methylbenzenesulfonyl)pipe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	7.4	n/a
Peking University					Assay Description Briefly, recombinant human GSK3β (1 �M, 10 �L) was mixed with 10 �L of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 �M), 19 �L of 2.5 ...				Bioorg Chem 61: 21-7 (2015) Article DOI: 10.1016/j.bioorg.2015.05.009 BindingDB Entry DOI: 10.7270/Q2N878HZ
Peking University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%