Affinity Data by PubMed id=26114810

PubMed code 26114810

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50115828 (CHEMBL3612132) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM7840 (RIVAROXABAN \| US8822458, 44 \| US8822458, 97) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor X (Homo sapiens (Human))	BDBM50115823 (CHEMBL3612128) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115827 (CHEMBL3612122) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115824 (CHEMBL3612126) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115826 (CHEMBL3612123) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of human F10a using S-2765 as substrate preincubated for 10 mins followed by substrate addition by microplate reader analysis				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50115827 (CHEMBL3612122) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of bovine plasma thrombin using S-2238 as substrate				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50115827 (CHEMBL3612122) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of trypsin (unknown origin) using S-2222 as substrate				Eur J Med Chem 101: 41-51 (2015) Article DOI: 10.1016/j.ejmech.2015.06.012 BindingDB Entry DOI: 10.7270/Q2TF004B
Southeast University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%