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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50322033 (2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of tryptase (unknown origin) using t-Boc-Phe-Ser-Arg-MCA as substrate after 5 mins by fluorimetric analysis | Bioorg Med Chem Lett 25: 3676-80 (2015) Article DOI: 10.1016/j.bmcl.2015.06.039 BindingDB Entry DOI: 10.7270/Q2416ZV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin (Homo sapiens (Human)) | BDBM50322033 (2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysis | Bioorg Med Chem Lett 25: 3676-80 (2015) Article DOI: 10.1016/j.bmcl.2015.06.039 BindingDB Entry DOI: 10.7270/Q2416ZV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50322033 (2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of thrombin (unknown origin) using t-Boc-Val-Pro-Arg-MCA as substrate after 5 mins by fluorimetric analysis | Bioorg Med Chem Lett 25: 3676-80 (2015) Article DOI: 10.1016/j.bmcl.2015.06.039 BindingDB Entry DOI: 10.7270/Q2416ZV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
