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PubMed code 26145818

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Oryctolagus cuniculus)		BDBM50098463
PNG
(CHEMBL3594037)
Show SMILES CC(=O)Oc1ccc2c(c1)occ(-c1ccc(NC(=O)COc3ccccc3)cc1)c2=O
Show InChI InChI=1S/C27H37N3O/c1-5-8-19-28-20-18-26(22(4)21-28)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)29(6-2)7-3/h5,8-17,22,26H,6-7,18-21H2,1-4H3/b8-5-/t22-,26+/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.52E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of CETP in rabbit serum incubated for 1 hr using NBD-labeled cholesterol in HDL and LDL by fluorescence based assay

Bioorg Med Chem 23: 4428-33 (2015)


Article DOI: 10.1016/j.bmc.2015.06.032
BindingDB Entry DOI: 10.7270/Q2P55Q8Q
More data for this
Ligand-Target Pair
Cholesteryl ester transfer protein


(Oryctolagus cuniculus)		BDBM50098467
PNG
(CHEMBL3594040)
Show SMILES CC(=O)Oc1ccc2c(c1)occ(-c1ccc(NC(=O)COc3ccccc3C)cc1)c2=O
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.42E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of CETP in rabbit serum incubated for 1 hr using NBD-labeled cholesterol in HDL and LDL by fluorescence based assay

Bioorg Med Chem 23: 4428-33 (2015)


Article DOI: 10.1016/j.bmc.2015.06.032
BindingDB Entry DOI: 10.7270/Q2P55Q8Q
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%