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PubMed code 26162498

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM50103898
PNG
(CHEMBL3594042)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c1ccccc1)c1ccnc2ccc(cc12)-c1ccc(O)cc1
Show InChI InChI=1S/C29H23N3O4S/c1-20(33)31-23-10-14-26(15-11-23)37(35,36)32(24-5-3-2-4-6-24)29-17-18-30-28-16-9-22(19-27(28)29)21-7-12-25(34)13-8-21/h2-19,34H,1H3,(H,31,33)
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Similars

Article
PubMed
n/an/a 613n/an/an/an/an/an/a



India; Academy of Scientific and Innovative Research

Curated by ChEMBL


Assay Description
Inhibition of mTOR (unknown origin) assessed as p70S6K phosphorylation after 30 mins by ELISA


Bioorg Med Chem 23: 4237-47 (2015)


Article DOI: 10.1016/j.bmc.2015.06.046
BindingDB Entry DOI: 10.7270/Q2D79D6T
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%