Affinity Data by PubMed id=26212777

PubMed code 26212777

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110727 (CHEMBL3605838) Show SMILES Nc1c2C3CCCCC3Sc2nc2CCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50279987 (2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-y...) Show SMILES Nc1c2CCCc2nc2CCCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110726 (CHEMBL3605836) Show SMILES Nc1c2CCCCc2nc2sccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50279987 (2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-y...) Show SMILES Nc1c2CCCc2nc2CCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110726 (CHEMBL3605836) Show SMILES Nc1c2CCCCc2nc2sccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM39664 ((6-bromo-1-butyl-2,3-dihydropyrrolo[2,3-b]quinolin...) Show SMILES CCCCN1CCc2c1nc1ccc(Br)cc1c2N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110699 (CHEMBL1531257) Show SMILES CC(=O)c1c(C)nc2ccccc2c1N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110727 (CHEMBL3605838) Show SMILES Nc1c2C3CCCCC3Sc2nc2CCCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110699 (CHEMBL1531257) Show SMILES CC(=O)c1c(C)nc2ccccc2c1N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50210319 (4-amino-6-methoxy-2-(trifluoromethyl)quinoline-3-c...) Show SMILES COc1ccc2nc(c(C#N)c(N)c2c1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110702 (CHEMBL283841) Show SMILES Nc1c2CCN(Cc3ccccc3)c2nc2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110728 (CHEMBL1617348) Show SMILES CN1CCc2c1nc1c(C)cccc1c2N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110702 (CHEMBL283841) Show SMILES Nc1c2CCN(Cc3ccccc3)c2nc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110722 (CHEMBL1478435) Show SMILES CC1(C)CC(=O)c2c(C1)nc1ccccc1c2N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50110701 (CHEMBL3605837) Show SMILES Nc1c2CCCc2nc2c3CCCc3nn12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM39664 ((6-bromo-1-butyl-2,3-dihydropyrrolo[2,3-b]quinolin...) Show SMILES CCCCN1CCc2c1nc1ccc(Br)cc1c2N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110728 (CHEMBL1617348) Show SMILES CN1CCc2c1nc1c(C)cccc1c2N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50210319 (4-amino-6-methoxy-2-(trifluoromethyl)quinoline-3-c...) Show SMILES COc1ccc2nc(c(C#N)c(N)c2c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110722 (CHEMBL1478435) Show SMILES CC1(C)CC(=O)c2c(C1)nc1ccccc1c2N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50110701 (CHEMBL3605837) Show SMILES Nc1c2CCCc2nc2c3CCCc3nn12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of equine serum BChE pre-incubated for 5 mins before butyrylthiocholineiodide substrate addition by Ellman's method				Bioorg Med Chem Lett 25: 3442-6 (2015) Article DOI: 10.1016/j.bmcl.2015.07.026 BindingDB Entry DOI: 10.7270/Q22B90TV
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%