Affinity Data by PubMed id=26214585

PubMed code 26214585

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163663 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	8.00E+3	-28.8	n/a	n/a	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
UDP-galactopyranose mutase (Caenorhabditis elegans (Roundworm))	BDBM163663 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.50E+4	-26.0	n/a	n/a	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
UDP-galactopyranose mutase (Mycobacterium tuberculosis H37Rv)	BDBM163663 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.10E+4	-25.5	n/a	n/a	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
UDP-galactopyranose mutase (Corynebacterium diphtheriae)	BDBM163663 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	7.70E+4	-23.2	n/a	n/a	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163657 (2‐[3‐(Furan‐2‐yl)‐6&...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.80E+4	-23.2	n/a	n/a	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163666 (2‐[3‐(Furan‐2‐yl)‐6&...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163669 (2‐{3‐[(4‐fluorophenyl)methyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163671 (2‐{3‐[(4‐Bromophenyl)methyl]R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163662 (2‐[6‐(4‐Chlorophenyl)‐7H&#...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163663 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163672 (2‐[3‐(4‐Chlorophenoxymethyl)R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163659 (2‐{3‐Cyclopropyl‐6‐phenyl&...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163660 (2‐[3‐(4‐Fluorophenyl)‐6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163665 (2‐[3‐(4‐Chlorophenoxymethyl)R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163667 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163670 (2‐{3‐[(4‐Fluorophenyl)methyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163657 (2‐[3‐(Furan‐2‐yl)‐6&...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163668 (2‐[6‐(4‐Chlorophenyl)‐3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163664 (2‐[3‐(2‐Methylfuran‐3̴...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163661 (2‐{3‐[(4‐Fluorophenyl)methyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163673 (3‐{2,5‐Dimethyl‐3‐[2‐...) Show SMILES Cc1cc(c(C)n1CCC([O-])=O)-c1csc(NCC=C)n1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison					Assay Description Polarization for the fluorescein-UDP conjugated probe in the presence of inhibitors was measured on a Tecan M1000 microplate reader, exciting with 47...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163657 (2‐[3‐(Furan‐2‐yl)‐6&...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison					Assay Description Polarization for the fluorescein-UDP conjugated probe in the presence of inhibitors was measured on a Tecan M1000 microplate reader, exciting with 47...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair
Probable UDP-galactopyranose mutase (Klebsiella pneumoniae (Enterobacteria))	BDBM163658 (2‐[6‐(4‐Fluorophenyl)‐3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	22
University of Wisconsin-Madison					Assay Description Reactions were performed in duplicate at 22�C in 50 mM NaH2PO4 buffer (pH 7) with 20 nM enzyme and 20 mM fresh sodium dithionite. Small molecules wer...				ACS Chem Biol 10: 2209-18 (2015) Article DOI: 10.1021/acschembio.5b00370 BindingDB Entry DOI: 10.7270/Q2FQ9VB4
University of Wisconsin-Madison					More data for this Ligand-Target Pair

* indicates data uncertainty>20%