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PubMed code 26231158

Compile data set for download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126165
PNG
(CHEMBL3629673)
Show SMILES Brc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8BrNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 8.51E+3n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126165
PNG
(CHEMBL3629673)
Show SMILES Brc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8BrNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 8.60E+3n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126164
PNG
(CHEMBL3416132)
Show SMILES Clc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8ClNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 1.62E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126164
PNG
(CHEMBL3416132)
Show SMILES Clc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8ClNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 1.62E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126169
PNG
(CHEMBL3629676)
Show SMILES Oc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H9NO2/c11-7-2-1-6-3-4-10-9(12)8(6)5-7/h1-2,5,11H,3-4H2,(H,10,12)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50339016
PNG
(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Show SMILES O=C1NCCc2ccccc12
Show InChI InChI=1S/C9H9NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-4H,5-6H2,(H,10,11)
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n/an/a 3.00E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126167
PNG
(CHEMBL3629675)
Show SMILES FC(F)(F)c1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H8F3NO/c11-10(12,13)7-2-1-6-3-4-14-9(15)8(6)5-7/h1-2,5H,3-4H2,(H,14,15)
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n/an/a 6.55E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126167
PNG
(CHEMBL3629675)
Show SMILES FC(F)(F)c1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H8F3NO/c11-10(12,13)7-2-1-6-3-4-14-9(15)8(6)5-7/h1-2,5H,3-4H2,(H,14,15)
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n/an/a 6.61E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126163
PNG
(CHEMBL3629672)
Show SMILES Fc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8FNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 7.24E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126163
PNG
(CHEMBL3629672)
Show SMILES Fc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8FNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 7.27E+4n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50339016
PNG
(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Show SMILES O=C1NCCc2ccccc12
Show InChI InChI=1S/C9H9NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-4H,5-6H2,(H,10,11)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126166
PNG
(CHEMBL3629674)
Show SMILES Cc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO/c1-7-2-3-8-4-5-11-10(12)9(8)6-7/h2-3,6H,4-5H2,1H3,(H,11,12)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126165
PNG
(CHEMBL3629673)
Show SMILES Brc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8BrNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126166
PNG
(CHEMBL3629674)
Show SMILES Cc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO/c1-7-2-3-8-4-5-11-10(12)9(8)6-7/h2-3,6H,4-5H2,1H3,(H,11,12)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126165
PNG
(CHEMBL3629673)
Show SMILES Brc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8BrNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126167
PNG
(CHEMBL3629675)
Show SMILES FC(F)(F)c1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H8F3NO/c11-10(12,13)7-2-1-6-3-4-14-9(15)8(6)5-7/h1-2,5H,3-4H2,(H,14,15)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126168
PNG
(CHEMBL3629677)
Show SMILES COc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO2/c1-13-8-3-2-7-4-5-11-10(12)9(7)6-8/h2-3,6H,4-5H2,1H3,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126164
PNG
(CHEMBL3416132)
Show SMILES Clc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8ClNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126164
PNG
(CHEMBL3416132)
Show SMILES Clc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8ClNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50126163
PNG
(CHEMBL3629672)
Show SMILES Fc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8FNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP1 (unknown origin) by fluorescence analysis

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126167
PNG
(CHEMBL3629675)
Show SMILES FC(F)(F)c1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H8F3NO/c11-10(12,13)7-2-1-6-3-4-14-9(15)8(6)5-7/h1-2,5H,3-4H2,(H,14,15)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126168
PNG
(CHEMBL3629677)
Show SMILES COc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO2/c1-13-8-3-2-7-4-5-11-10(12)9(7)6-8/h2-3,6H,4-5H2,1H3,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126163
PNG
(CHEMBL3629672)
Show SMILES Fc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C9H8FNO/c10-7-2-1-6-3-4-11-9(12)8(6)5-7/h1-2,5H,3-4H2,(H,11,12)
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Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126166
PNG
(CHEMBL3629674)
Show SMILES Cc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO/c1-7-2-3-8-4-5-11-10(12)9(8)6-7/h2-3,6H,4-5H2,1H3,(H,11,12)
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n/an/a 1.12E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126166
PNG
(CHEMBL3629674)
Show SMILES Cc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO/c1-7-2-3-8-4-5-11-10(12)9(8)6-7/h2-3,6H,4-5H2,1H3,(H,11,12)
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n/an/a 1.12E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50339016
PNG
(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Show SMILES O=C1NCCc2ccccc12
Show InChI InChI=1S/C9H9NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-4H,5-6H2,(H,10,11)
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n/an/a 1.29E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50339016
PNG
(3,4-dihydroisoquinolin-1(2H)-one | CHEMBL1688212)
Show SMILES O=C1NCCc2ccccc12
Show InChI InChI=1S/C9H9NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-4H,5-6H2,(H,10,11)
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n/an/a 1.30E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126168
PNG
(CHEMBL3629677)
Show SMILES COc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO2/c1-13-8-3-2-7-4-5-11-10(12)9(7)6-8/h2-3,6H,4-5H2,1H3,(H,11,12)
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n/an/a 1.70E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10


(Homo sapiens (Human))		BDBM50126168
PNG
(CHEMBL3629677)
Show SMILES COc1ccc2CCNC(=O)c2c1
Show InChI InChI=1S/C10H11NO2/c1-13-8-3-2-7-4-5-11-10(12)9(7)6-8/h2-3,6H,4-5H2,1H3,(H,11,12)
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MCE
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n/an/a 1.72E+5n/an/an/an/an/an/a



Oregon Health& Science University

Curated by ChEMBL


Assay Description
Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrate

Bioorg Med Chem Lett 25: 4770-3 (2015)


Article DOI: 10.1016/j.bmcl.2015.07.033
BindingDB Entry DOI: 10.7270/Q23R0VQW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%