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PubMed code 26270954

Compile data set for download or QSAR
Found 7 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104743
PNG
(CHEMBL3126299)
Show SMILES Oc1cccc2oc(CCCc3ccccc3)cc(=O)c12
Show InChI InChI=1S/C18H16O3/c19-15-10-5-11-17-18(15)16(20)12-14(21-17)9-4-8-13-6-2-1-3-7-13/h1-3,5-7,10-12,19H,4,8-9H2
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 251n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104741
PNG
(CHEMBL3126302)
Show SMILES Oc1cccc2oc(CCc3cccs3)cc(=O)c12
Show InChI InChI=1S/C15H12O3S/c16-12-4-1-5-14-15(12)13(17)9-10(18-14)6-7-11-3-2-8-19-11/h1-5,8-9,16H,6-7H2
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PubMed
 1.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104740
PNG
(CHEMBL3593950)
Show SMILES Oc1ccc(CCc2cc(=O)c3c(O)cccc3o2)cc1
Show InChI InChI=1S/C17H14O4/c18-12-7-4-11(5-8-12)6-9-13-10-15(20)17-14(19)2-1-3-16(17)21-13/h1-5,7-8,10,18-19H,6,9H2
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PubMed
 1.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104739
PNG
(CHEMBL3593949)
Show SMILES Oc1cccc(CCc2cc(=O)c3c(O)cccc3o2)c1
Show InChI InChI=1S/C17H14O4/c18-12-4-1-3-11(9-12)7-8-13-10-15(20)17-14(19)5-2-6-16(17)21-13/h1-6,9-10,18-19H,7-8H2
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PubMed
 1.26E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104744
PNG
(CHEMBL3593952)
Show SMILES Oc1cccc2oc(COCc3ccccc3)cc(=O)c12
Show InChI InChI=1S/C17H14O4/c18-14-7-4-8-16-17(14)15(19)9-13(21-16)11-20-10-12-5-2-1-3-6-12/h1-9,18H,10-11H2
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PubMed
 1.59E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104742
PNG
(CHEMBL3593951)
Show SMILES Oc1cccc2oc(CCc3ccco3)cc(=O)c12
Show InChI InChI=1S/C15H12O4/c16-12-4-1-5-14-15(12)13(17)9-11(19-14)7-6-10-3-2-8-18-10/h1-5,8-9,16H,6-7H2
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PubMed
 2.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50104738
PNG
(CHEMBL3126297)
Show SMILES Oc1cccc2oc(COc3ccccc3)cc(=O)c12
Show InChI InChI=1S/C16H12O4/c17-13-7-4-8-15-16(13)14(18)9-12(20-15)10-19-11-5-2-1-3-6-11/h1-9,17H,10H2
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<1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT2B receptor expressed in stable HEK cells membranes

J Nat Prod 78: 1859-67 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00118
BindingDB Entry DOI: 10.7270/Q27H1MB8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%