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PubMed code 26314925

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117841
PNG
(CHEMBL3613983)
Show SMILES Brc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C23H23BrN2O4S/c24-20-8-6-19(7-9-20)16-25-23(27)17-30-21-10-12-22(13-11-21)31(28,29)26-15-14-18-4-2-1-3-5-18/h1-13,26H,14-17H2,(H,25,27)
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n/an/a 2.10E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117832
PNG
(CHEMBL3613975)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C23H23ClN2O4S/c24-20-8-6-19(7-9-20)16-25-23(27)17-30-21-10-12-22(13-11-21)31(28,29)26-15-14-18-4-2-1-3-5-18/h1-13,26H,14-17H2,(H,25,27)
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n/an/a 5.20E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117840
PNG
(CHEMBL3612087)
Show SMILES COc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C24H26N2O5S/c1-30-21-9-7-20(8-10-21)17-25-24(27)18-31-22-11-13-23(14-12-22)32(28,29)26-16-15-19-5-3-2-4-6-19/h2-14,26H,15-18H2,1H3,(H,25,27)
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n/an/a 5.90E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117845
PNG
(CHEMBL3613987)
Show SMILES Clc1ccc(NC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C22H21ClN2O4S/c23-18-6-8-19(9-7-18)25-22(26)16-29-20-10-12-21(13-11-20)30(27,28)24-15-14-17-4-2-1-3-5-17/h1-13,24H,14-16H2,(H,25,26)
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n/an/a 6.60E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117842
PNG
(CHEMBL3613984)
Show SMILES Fc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C23H23FN2O4S/c24-20-8-6-19(7-9-20)16-25-23(27)17-30-21-10-12-22(13-11-21)31(28,29)26-15-14-18-4-2-1-3-5-18/h1-13,26H,14-17H2,(H,25,27)
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n/an/a 8.10E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117853
PNG
(CHEMBL3613995)
Show SMILES COc1cccc(NC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)c1
Show InChI InChI=1S/C23H24N2O5S/c1-29-21-9-5-8-19(16-21)25-23(26)17-30-20-10-12-22(13-11-20)31(27,28)24-15-14-18-6-3-2-4-7-18/h2-13,16,24H,14-15,17H2,1H3,(H,25,26)
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n/an/a 9.20E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117846
PNG
(CHEMBL3613988)
Show SMILES Fc1ccc(NC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C22H21FN2O4S/c23-18-6-8-19(9-7-18)25-22(26)16-29-20-10-12-21(13-11-20)30(27,28)24-15-14-17-4-2-1-3-5-17/h1-13,24H,14-16H2,(H,25,26)
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n/an/a 1.05E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117848
PNG
(CHEMBL3613990)
Show SMILES COc1ccccc1NC(=O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Show InChI InChI=1S/C23H24N2O5S/c1-29-22-10-6-5-9-21(22)25-23(26)17-30-19-11-13-20(14-12-19)31(27,28)24-16-15-18-7-3-2-4-8-18/h2-14,24H,15-17H2,1H3,(H,25,26)
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n/an/a 1.42E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117844
PNG
(CHEMBL3613986)
Show SMILES O=C(COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1)Nc1ccccc1
Show InChI InChI=1S/C22H22N2O4S/c25-22(24-19-9-5-2-6-10-19)17-28-20-11-13-21(14-12-20)29(26,27)23-16-15-18-7-3-1-4-8-18/h1-14,23H,15-17H2,(H,24,25)
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n/an/a 1.47E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117843
PNG
(CHEMBL3613985)
Show SMILES Fc1cccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)c1
Show InChI InChI=1S/C23H23FN2O4S/c24-20-8-4-7-19(15-20)16-25-23(27)17-30-21-9-11-22(12-10-21)31(28,29)26-14-13-18-5-2-1-3-6-18/h1-12,15,26H,13-14,16-17H2,(H,25,27)
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n/an/a 1.56E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117839
PNG
(CHEMBL3613982)
Show SMILES O=C(COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1)NCc1ccccc1
Show InChI InChI=1S/C23H24N2O4S/c26-23(24-17-20-9-5-2-6-10-20)18-29-21-11-13-22(14-12-21)30(27,28)25-16-15-19-7-3-1-4-8-19/h1-14,25H,15-18H2,(H,24,26)
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n/an/a 2.31E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117847
PNG
(CHEMBL3613989)
Show SMILES COc1ccc(NC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C23H24N2O5S/c1-29-20-9-7-19(8-10-20)25-23(26)17-30-21-11-13-22(14-12-21)31(27,28)24-16-15-18-5-3-2-4-6-18/h2-14,24H,15-17H2,1H3,(H,25,26)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117836
PNG
(CHEMBL3613979)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C22H20Cl2N2O4S/c23-18-5-1-16(2-6-18)13-25-22(27)15-30-20-9-11-21(12-10-20)31(28,29)26-14-17-3-7-19(24)8-4-17/h1-12,26H,13-15H2,(H,25,27)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117838
PNG
(CHEMBL3613981)
Show SMILES O=C(COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1)NCCc1ccccc1
Show InChI InChI=1S/C24H26N2O4S/c27-24(25-17-15-20-7-3-1-4-8-20)19-30-22-11-13-23(14-12-22)31(28,29)26-18-16-21-9-5-2-6-10-21/h1-14,26H,15-19H2,(H,25,27)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117850
PNG
(CHEMBL3613992)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Show InChI InChI=1S/C22H21N3O6S/c26-22(24-20-8-4-5-9-21(20)25(27)28)16-31-18-10-12-19(13-11-18)32(29,30)23-15-14-17-6-2-1-3-7-17/h1-13,23H,14-16H2,(H,24,26)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117834
PNG
(CHEMBL3613977)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)C(=O)Nc2ccncc2)cc1
Show InChI InChI=1S/C21H18ClN3O3/c22-17-5-1-15(2-6-17)13-24-20(26)14-28-19-7-3-16(4-8-19)21(27)25-18-9-11-23-12-10-18/h1-12H,13-14H2,(H,24,26)(H,23,25,27)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117849
PNG
(CHEMBL3613991)
Show SMILES Cc1ccccc1NC(=O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Show InChI InChI=1S/C23H24N2O4S/c1-18-7-5-6-10-22(18)25-23(26)17-29-20-11-13-21(14-12-20)30(27,28)24-16-15-19-8-3-2-4-9-19/h2-14,24H,15-17H2,1H3,(H,25,26)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117837
PNG
(CHEMBL3613980)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)Nc2ccccc2)cc1
Show InChI InChI=1S/C21H19ClN2O4S/c22-17-8-6-16(7-9-17)14-23-21(25)15-28-19-10-12-20(13-11-19)29(26,27)24-18-4-2-1-3-5-18/h1-13,24H,14-15H2,(H,23,25)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117851
PNG
(CHEMBL3613993)
Show SMILES O=C(COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1)Nc1ccccc1C#N
Show InChI InChI=1S/C23H21N3O4S/c24-16-19-8-4-5-9-22(19)26-23(27)17-30-20-10-12-21(13-11-20)31(28,29)25-15-14-18-6-2-1-3-7-18/h1-13,25H,14-15,17H2,(H,26,27)
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Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117833
PNG
(CHEMBL3613976)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)C(=O)NCCc2ccccc2)cc1
Show InChI InChI=1S/C24H23ClN2O3/c25-21-10-6-19(7-11-21)16-27-23(28)17-30-22-12-8-20(9-13-22)24(29)26-15-14-18-4-2-1-3-5-18/h1-13H,14-17H2,(H,26,29)(H,27,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117852
PNG
(CHEMBL3613994)
Show SMILES FC(F)(F)Oc1ccccc1NC(=O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Show InChI InChI=1S/C23H21F3N2O5S/c24-23(25,26)33-21-9-5-4-8-20(21)28-22(29)16-32-18-10-12-19(13-11-18)34(30,31)27-15-14-17-6-2-1-3-7-17/h1-13,27H,14-16H2,(H,28,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117835
PNG
(CHEMBL3613978)
Show SMILES Clc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCCc2ccccc2)cc1
Show InChI InChI=1S/C24H25ClN2O4S/c25-21-10-8-20(9-11-21)17-26-24(28)18-31-22-12-14-23(15-13-22)32(29,30)27-16-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-15,27H,4,7,16-18H2,(H,26,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117854
PNG
(CHEMBL3613996)
Show SMILES COc1cc(F)ccc1NC(=O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Show InChI InChI=1S/C23H23FN2O5S/c1-30-22-15-18(24)7-12-21(22)26-23(27)16-31-19-8-10-20(11-9-19)32(28,29)25-14-13-17-5-3-2-4-6-17/h2-12,15,25H,13-14,16H2,1H3,(H,26,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
Phosphatidylcholine:ceramide cholinephosphotransferase 1


(Homo sapiens (Human))		BDBM50117855
PNG
(CHEMBL3613997)
Show SMILES [K+].[H][C@]12C[C@@H](OC([S-])=S)[C@]([H])(C1)[C@@]1([H])CCC[C@@]21[H] |r,THB:5:4:17.12:11|
Show InChI InChI=1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1/t6-,7-,8-,9+,10+;/m0./s1
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n/an/a 2.19E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...

Bioorg Med Chem 23: 6173-84 (2015)


Article DOI: 10.1016/j.bmc.2015.07.060
BindingDB Entry DOI: 10.7270/Q2NG4SF6
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%