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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Hunan University of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant COX-2 using arachidonic acid after 15 mins by fluorescence based assay | Bioorg Med Chem Lett 25: 4082-4 (2015) Article DOI: 10.1016/j.bmcl.2015.08.034 BindingDB Entry DOI: 10.7270/Q25X2BR7 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hunan University of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 using arachidonic acid after 15 mins by fluorescence based assay | Bioorg Med Chem Lett 25: 4082-4 (2015) Article DOI: 10.1016/j.bmcl.2015.08.034 BindingDB Entry DOI: 10.7270/Q25X2BR7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
