Affinity Data by PubMed id=26331426

PubMed code 26331426

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127007 (CHEMBL3628038) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127009 (CHEMBL3628243) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127008 (CHEMBL3628241) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127006 (CHEMBL3628036) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127010 (CHEMBL3628244) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127003 (CHEMBL2062865) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127003 (CHEMBL2062865) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U373MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127005 (CHEMBL3628032) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U373MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127005 (CHEMBL3628032) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127004 (CHEMBL2062868 \| Vernolide-B) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U251MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50127004 (CHEMBL2062868 \| Vernolide-B) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Hilo Curated by ChEMBL					Assay Description Inhibition of Stat3 dimer DNA binding activity in human U373MG cells nuclear extract after 1.5 hrs by EMSA using radiolabeled probe hSIE				J Med Chem 58: 7734-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00686 BindingDB Entry DOI: 10.7270/Q2Z321GS
University of Hawaii at Hilo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%