Affinity Data by PubMed id=26372652

PubMed code 26372652

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human))	BDBM50124574 (CHEMBL3623737) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human))	BDBM50124577 (CHEMBL3623738) Show SMILES OC(=O)c1ccccc1Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human))	BDBM50124575 (CHEMBL3623735) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human))	BDBM50124576 (CHEMBL3623736) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Homo sapiens (Human))	BDBM50124577 (CHEMBL3623738) Show SMILES OC(=O)c1ccccc1Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Homo sapiens (Human))	BDBM50124575 (CHEMBL3623735) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50124575 (CHEMBL3623735) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50124575 (CHEMBL3623735) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Homo sapiens (Human))	BDBM50124576 (CHEMBL3623736) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Homo sapiens (Human))	BDBM50124574 (CHEMBL3623737) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrate				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50124577 (CHEMBL3623738) Show SMILES OC(=O)c1ccccc1Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50124577 (CHEMBL3623738) Show SMILES OC(=O)c1ccccc1Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50124574 (CHEMBL3623737) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50124576 (CHEMBL3623736) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50124576 (CHEMBL3623736) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50124574 (CHEMBL3623737) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assay				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Acid-sensing ion channel 5 (Rattus norvegicus)	BDBM50124575 (CHEMBL3623735) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+6	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytes				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Acid-sensing ion channel 5 (Rattus norvegicus)	BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid \|...) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+6	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytes				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Acid-sensing ion channel 5 (Rattus norvegicus)	BDBM50124577 (CHEMBL3623738) Show SMILES OC(=O)c1ccccc1Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+6	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytes				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Acid-sensing ion channel 5 (Rattus norvegicus)	BDBM50124574 (CHEMBL3623737) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+6	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytes				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair
Acid-sensing ion channel 5 (Rattus norvegicus)	BDBM50124576 (CHEMBL3623736) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+6	n/a	n/a	n/a	n/a
RWTH Aachen University Curated by ChEMBL					Assay Description Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytes				Bioorg Med Chem Lett 25: 4437-40 (2015) Article DOI: 10.1016/j.bmcl.2015.09.012 BindingDB Entry DOI: 10.7270/Q2M04786
RWTH Aachen University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%