Affinity Data by PubMed id=26376355

PubMed code 26376355

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin)				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin)				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50293360 (CHEMBL556532 \| N-Hydroxy-E-3-(biphenyl-4-yl)-acryl...) Show SMILES ONC(=O)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124587 (CHEMBL3621537) Show SMILES ONC(=O)N\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50124587 (CHEMBL3621537) Show SMILES ONC(=O)N\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin)				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50124587 (CHEMBL3621537) Show SMILES ONC(=O)N\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin)				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124588 (CHEMBL3621538) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124624 (CHEMBL3621541) Show SMILES ON1CC\C(=C/c2ccc(cc2)-c2ccccc2)C1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124590 (CHEMBL3621540) Show SMILES N#CSC\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124589 (CHEMBL3621539) Show SMILES CC(=O)SCC(=O)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124586 (CHEMBL3621536) Show SMILES NNC(=O)N\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124585 (CHEMBL3621535) Show SMILES NNC(=O)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50124584 (CHEMBL3621534) Show SMILES OC(=O)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of human HDAC2 after 40 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 4457-60 (2015) Article DOI: 10.1016/j.bmcl.2015.09.006 BindingDB Entry DOI: 10.7270/Q2BG2QTR
University of Milan Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%