Affinity Data by PubMed id=26432604

PubMed code 26432604

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498947 (Rose bengal sodium) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recordi...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498947 (Rose bengal sodium) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498946 (CHEMBL3735815) Show SMILES CCCCCCC1c2ccc(O)cc2Oc2cc(O)ccc12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recordi...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 2 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498947 (Rose bengal sodium) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA2 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498948 (CHEMBL3736159) Show SMILES Oc1ccc2C(C3CCCC3)c3ccc(O)cc3Oc2c1 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recordi...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498946 (CHEMBL3735815) Show SMILES CCCCCCC1c2ccc(O)cc2Oc2cc(O)ccc12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposome dependent proOmpA translocation incubated for 1.5 hrs measured by Western blot analysis				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 2 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498946 (CHEMBL3735815) Show SMILES CCCCCCC1c2ccc(O)cc2Oc2cc(O)ccc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA2 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498946 (CHEMBL3735815) Show SMILES CCCCCCC1c2ccc(O)cc2Oc2cc(O)ccc12 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 2 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498948 (CHEMBL3736159) Show SMILES Oc1ccc2C(C3CCCC3)c3ccc(O)cc3Oc2c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA2 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein translocase subunit SecA 1 (Staphylococcus aureus (strain NCTC 8325))	BDBM50498948 (CHEMBL3736159) Show SMILES Oc1ccc2C(C3CCCC3)c3ccc(O)cc3Oc2c1 Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...				Bioorg Med Chem 23: 7061-8 (2015) Article DOI: 10.1016/j.bmc.2015.09.027 BindingDB Entry DOI: 10.7270/Q2WS8X7Z
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%