Affinity Data by PubMed id=26435514

PubMed code 26435514

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492518 (Florbetapir \| US10906900, AV45) Show SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500796 (CHEMBL3760007) Show SMILES CN(C)c1ccc(OCc2ccc(OCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500797 (CHEMBL3758709) Show SMILES CN(C)c1ccc(COc2ccc(OCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122787 (2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(I)ccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50129793 (2-(4''-methylaminophenyl)-6-hydroxybenzothiazole \|...) Show SMILES CNc1ccc(cc1)-c1nc2ccc(O)cc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500791 (CHEMBL3759263) Show SMILES COc1ccc(COc2ccc(OCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500792 (CHEMBL3758500) Show SMILES COc1ccc(OCc2ccc(OCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	153	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500793 (CHEMBL3758630) Show SMILES CN(C)c1ccc(COc2ccc(OCCOCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500798 (CHEMBL3759510) Show SMILES CN(C)c1ccc(COc2ccc(OCCOCCOCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	358	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500794 (CHEMBL3759176) Show SMILES COc1ccc(COc2ccc(OCCOCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	438	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50500795 (CHEMBL3759854) Show SMILES COc1ccc(COc2ccc(OCCOCCOCCF)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Normal University Curated by ChEMBL					Assay Description Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)				Eur J Med Chem 104: 86-96 (2015) Article DOI: 10.1016/j.ejmech.2015.09.028 BindingDB Entry DOI: 10.7270/Q22R3VP8
Beijing Normal University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%