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PubMed code 26483137

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA gyrase subunit A/B


(Staphylococcus aureus)
BDBM50329257
PNG
(2-Hexadecynoic acid | CHEMBL1269411)
Show SMILES CCCCCCCCCCCCCCC#CC(O)=O
Show InChI InChI=1S/C17H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19/h2-14H2,1H3,(H,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Inter American University of Puerto Rico

Curated by ChEMBL


Assay Description
Inhibition of supercoiling activity of Staphylococcus aureus DNA gyrase using relaxed pHOT1 plasmid DNA after 60 mins using ethidium bromide staining...


Bioorg Med Chem Lett 25: 5067-71 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.022
BindingDB Entry DOI: 10.7270/Q2GF0WBP
More data for this
Ligand-Target Pair
DNA gyrase subunit A/B


(Staphylococcus aureus)
BDBM50133156
PNG
(CHEMBL3634703)
Show SMILES CCCCCCCCCCCCCC#CC(=O)Oc1ccc(\C=C\C(=O)\C=C\c2ccc(OC(=O)C#CCCCCCCCCCCCCC)c(OC)c2)cc1OC
Show InChI InChI=1S/C51H70O7/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-50(53)57-46-39-35-43(41-48(46)55-3)33-37-45(52)38-34-44-36-40-47(49(42-44)56-4)58-51(54)32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h33-42H,5-28H2,1-4H3/b37-33+,38-34+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Inter American University of Puerto Rico

Curated by ChEMBL


Assay Description
Inhibition of supercoiling activity of Staphylococcus aureus DNA gyrase using relaxed pHOT1 plasmid DNA after 60 mins using ethidium bromide staining...


Bioorg Med Chem Lett 25: 5067-71 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.022
BindingDB Entry DOI: 10.7270/Q2GF0WBP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%