BindingDB logo
myBDB logout

PubMed code 26506089

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499614
PNG
(CHEMBL3741938)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C33H37IN3O7P/c1-22(23-12-18-27(19-13-23)44-45(41,42)43)21-29(38)35-30(33(2,3)4)32(40)36-20-8-11-28(36)31(39)37(25-9-6-5-7-10-25)26-16-14-24(34)15-17-26/h5-7,9-10,12-19,21,28,30H,8,11,20H2,1-4H3,(H,35,38)(H2,41,42,43)/b22-21+/t28-,30+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499605
PNG
(CHEMBL3741162)
Show SMILES CC(C)(C)[C@H](NC(=O)\C=C\c1ccc(OP(O)(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1 |r|
Show InChI InChI=1S/C32H35IN3O7P/c1-32(2,3)29(34-28(37)20-13-22-11-18-26(19-12-22)43-44(40,41)42)31(39)35-21-7-10-27(35)30(38)36(24-8-5-4-6-9-24)25-16-14-23(33)15-17-25/h4-6,8-9,11-20,27,29H,7,10,21H2,1-3H3,(H,34,37)(H2,40,41,42)/b20-13+/t27-,29+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499625
PNG
(CHEMBL3741886)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C33H38N3O7P/c1-23(24-17-19-27(20-18-24)43-44(40,41)42)22-29(37)34-30(33(2,3)4)32(39)35-21-11-16-28(35)31(38)36(25-12-7-5-8-13-25)26-14-9-6-10-15-26/h5-10,12-15,17-20,22,28,30H,11,16,21H2,1-4H3,(H,34,37)(H2,40,41,42)/b23-22+/t28-,30+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 89n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499608
PNG
(CHEMBL3739524)
Show SMILES CN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C28H36N3O7P/c1-19(20-13-15-22(16-14-20)38-39(35,36)37)18-24(32)29-25(28(2,3)4)27(34)31-17-9-12-23(31)26(33)30(5)21-10-7-6-8-11-21/h6-8,10-11,13-16,18,23,25H,9,12,17H2,1-5H3,(H,29,32)(H2,35,36,37)/b19-18+/t23-,25+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499597
PNG
(CHEMBL3741674)
Show SMILES C[C@H](NC(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C)C(=O)N(C)c1ccccc1 |r|
Show InChI InChI=1S/C26H34N3O7P/c1-17(19-12-14-21(15-13-19)36-37(33,34)35)16-22(30)28-23(26(3,4)5)24(31)27-18(2)25(32)29(6)20-10-8-7-9-11-20/h7-16,18,23H,1-6H3,(H,27,31)(H,28,30)(H2,33,34,35)/b17-16+/t18-,23+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499624
PNG
(CHEMBL3740709)
Show SMILES CC(C)(C)[C@H](NC(=O)\C=C\c1ccc(OP(O)(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C32H36N3O7P/c1-32(2,3)29(33-28(36)21-18-23-16-19-26(20-17-23)42-43(39,40)41)31(38)34-22-10-15-27(34)30(37)35(24-11-6-4-7-12-24)25-13-8-5-9-14-25/h4-9,11-14,16-21,27,29H,10,15,22H2,1-3H3,(H,33,36)(H2,39,40,41)/b21-18+/t27-,29+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499604
PNG
(CHEMBL3742125)
Show SMILES CC(C)(C)[C@H](NC(=O)c1cc2cc(OP(O)(O)=O)ccc2[nH]1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1 |r|
Show InChI InChI=1S/C32H34IN4O7P/c1-32(2,3)28(35-29(38)26-19-20-18-24(44-45(41,42)43)15-16-25(20)34-26)31(40)36-17-7-10-27(36)30(39)37(22-8-5-4-6-9-22)23-13-11-21(33)12-14-23/h4-6,8-9,11-16,18-19,27-28,34H,7,10,17H2,1-3H3,(H,35,38)(H2,41,42,43)/t27-,28+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499626
PNG
(CHEMBL3741189)
Show SMILES CN(C1CCCCC1)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C |r|
Show InChI InChI=1S/C28H42N3O7P/c1-19(20-13-15-22(16-14-20)38-39(35,36)37)18-24(32)29-25(28(2,3)4)27(34)31-17-9-12-23(31)26(33)30(5)21-10-7-6-8-11-21/h13-16,18,21,23,25H,6-12,17H2,1-5H3,(H,29,32)(H2,35,36,37)/b19-18+/t23-,25+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499612
PNG
(CHEMBL3739968)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C29H38N3O7P/c1-20(22-12-14-23(15-13-22)39-40(36,37)38)19-25(33)31-26(29(2,3)4)28(35)32-18-8-11-24(32)27(34)30-17-16-21-9-6-5-7-10-21/h5-7,9-10,12-15,19,24,26H,8,11,16-18H2,1-4H3,(H,30,34)(H,31,33)(H2,36,37,38)/b20-19+/t24-,26+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499620
PNG
(CHEMBL3741243)
Show SMILES CN(CC(=O)N(C)c1ccccc1)C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C |r|
Show InChI InChI=1S/C26H34N3O7P/c1-18(19-12-14-21(15-13-19)36-37(33,34)35)16-22(30)27-24(26(2,3)4)25(32)28(5)17-23(31)29(6)20-10-8-7-9-11-20/h7-16,24H,17H2,1-6H3,(H,27,30)(H2,33,34,35)/b18-16+/t24-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499609
PNG
(CHEMBL3740710)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C27H34N3O7P/c1-18(19-12-14-21(15-13-19)37-38(34,35)36)17-23(31)29-24(27(2,3)4)26(33)30-16-8-11-22(30)25(32)28-20-9-6-5-7-10-20/h5-7,9-10,12-15,17,22,24H,8,11,16H2,1-4H3,(H,28,32)(H,29,31)(H2,34,35,36)/b18-17+/t22-,24+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499633
PNG
(CHEMBL3739875)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C28H36N3O7P/c1-19(21-12-14-22(15-13-21)38-39(35,36)37)17-24(32)30-25(28(2,3)4)27(34)31-16-8-11-23(31)26(33)29-18-20-9-6-5-7-10-20/h5-7,9-10,12-15,17,23,25H,8,11,16,18H2,1-4H3,(H,29,33)(H,30,32)(H2,35,36,37)/b19-17+/t23-,25+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499610
PNG
(CHEMBL3739525)
Show SMILES CCN(CC)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C |r|
Show InChI InChI=1S/C25H38N3O7P/c1-7-27(8-2)23(30)20-10-9-15-28(20)24(31)22(25(4,5)6)26-21(29)16-17(3)18-11-13-19(14-12-18)35-36(32,33)34/h11-14,16,20,22H,7-10,15H2,1-6H3,(H,26,29)(H2,32,33,34)/b17-16+/t20-,22+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 380n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499616
PNG
(CHEMBL3742269)
Show SMILES CN(CC1CCCN1C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C28H38N3O6P/c1-20(21-13-15-24(16-14-21)37-38(34,35)36)18-25(32)29-26(28(2,3)4)27(33)31-17-9-12-23(31)19-30(5)22-10-7-6-8-11-22/h6-8,10-11,13-16,18,23,26H,9,12,17,19H2,1-5H3,(H,29,32)(H2,34,35,36)/b20-18+/t23?,26-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499598
PNG
(CHEMBL3740699)
Show SMILES C[C@H](N(C)C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C)C(=O)N(C)c1ccccc1 |r|
Show InChI InChI=1S/C27H36N3O7P/c1-18(20-13-15-22(16-14-20)37-38(34,35)36)17-23(31)28-24(27(3,4)5)26(33)29(6)19(2)25(32)30(7)21-11-9-8-10-12-21/h8-17,19,24H,1-7H3,(H,28,31)(H2,34,35,36)/b18-17+/t19-,24+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499611
PNG
(CHEMBL3740610)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCCC1\C=C\CCc1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C30H39N2O6P/c1-22(24-16-18-26(19-17-24)38-39(35,36)37)21-27(33)31-28(30(2,3)4)29(34)32-20-10-15-25(32)14-9-8-13-23-11-6-5-7-12-23/h5-7,9,11-12,14,16-19,21,25,28H,8,10,13,15,20H2,1-4H3,(H,31,33)(H2,35,36,37)/b14-9+,22-21+/t25?,28-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499618
PNG
(CHEMBL3741667)
Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)\C=C(/C)c1ccc(OP(O)(O)=O)cc1)C(C)(C)C |r|
Show InChI InChI=1S/C23H34N3O7P/c1-15(16-9-11-17(12-10-16)33-34(30,31)32)14-19(27)24-20(23(2,3)4)22(29)26-13-7-8-18(26)21(28)25(5)6/h9-12,14,18,20H,7-8,13H2,1-6H3,(H,24,27)(H2,30,31,32)/b15-14+/t18-,20+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 740n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499606
PNG
(CHEMBL3740611)
Show SMILES CN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)\C=C\c1ccc(OP(O)(O)=O)cc1)C(C)(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C27H34N3O7P/c1-27(2,3)24(28-23(31)17-14-19-12-15-21(16-13-19)37-38(34,35)36)26(33)30-18-8-11-22(30)25(32)29(4)20-9-6-5-7-10-20/h5-7,9-10,12-17,22,24H,8,11,18H2,1-4H3,(H,28,31)(H2,34,35,36)/b17-14+/t22-,24+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 870n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499629
PNG
(CHEMBL3739599)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCCC1CCCCc1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C30H41N2O6P/c1-22(24-16-18-26(19-17-24)38-39(35,36)37)21-27(33)31-28(30(2,3)4)29(34)32-20-10-15-25(32)14-9-8-13-23-11-6-5-7-12-23/h5-7,11-12,16-19,21,25,28H,8-10,13-15,20H2,1-4H3,(H,31,33)(H2,35,36,37)/b22-21+/t25?,28-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.07E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499607
PNG
(CHEMBL3741852)
Show SMILES CC(C)(C)[C@H](NC(=O)\C=C\c1ccc(OP(O)(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1 |r|
Show InChI InChI=1S/C26H32N3O7P/c1-26(2,3)23(28-22(30)16-13-18-11-14-20(15-12-18)36-37(33,34)35)25(32)29-17-7-10-21(29)24(31)27-19-8-5-4-6-9-19/h4-6,8-9,11-16,21,23H,7,10,17H2,1-3H3,(H,27,31)(H,28,30)(H2,33,34,35)/b16-13+/t21-,23+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.25E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499630
PNG
(CHEMBL3740569)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(N)=O |r|
Show InChI InChI=1S/C52H78N11O16P/c1-6-30(4)44(45(55)68)62-50(73)37(25-29(2)3)59-49(72)40(28-43(66)67)60-46(69)35(21-22-42(54)65)57-48(71)39(26-32-13-8-7-9-14-32)61-51(74)41-16-12-24-63(41)52(75)36(15-10-11-23-53)58-47(70)38(56-31(5)64)27-33-17-19-34(20-18-33)79-80(76,77)78/h7-9,13-14,17-20,29-30,35-41,44H,6,10-12,15-16,21-28,53H2,1-5H3,(H2,54,65)(H2,55,68)(H,56,64)(H,57,71)(H,58,70)(H,59,72)(H,60,69)(H,61,74)(H,62,73)(H,66,67)(H2,76,77,78)/t30-,35-,36-,37-,38-,39-,40-,41-,44-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499631
PNG
(CHEMBL3740952)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(N)=O |r|
Show InChI InChI=1S/C46H67N10O15P/c1-26(2)22-33(40(49)61)53-44(65)36(25-39(59)60)54-41(62)31(18-19-38(48)58)51-43(64)35(23-28-10-5-4-6-11-28)55-45(66)37-13-9-21-56(37)46(67)32(12-7-8-20-47)52-42(63)34(50-27(3)57)24-29-14-16-30(17-15-29)71-72(68,69)70/h4-6,10-11,14-17,26,31-37H,7-9,12-13,18-25,47H2,1-3H3,(H2,48,58)(H2,49,61)(H,50,57)(H,51,64)(H,52,63)(H,53,65)(H,54,62)(H,55,66)(H,59,60)(H2,68,69,70)/t31-,32-,33-,34-,35-,36-,37-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499627
PNG
(CHEMBL3741476)
Show SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCCC1\C=C\c1ccccc1)C(C)(C)C)c1ccc(OP(O)(O)=O)cc1 |r|
Show InChI InChI=1S/C28H35N2O6P/c1-20(22-13-16-24(17-14-22)36-37(33,34)35)19-25(31)29-26(28(2,3)4)27(32)30-18-8-11-23(30)15-12-21-9-6-5-7-10-21/h5-7,9-10,12-17,19,23,26H,8,11,18H2,1-4H3,(H,29,31)(H2,33,34,35)/b15-12+,20-19+/t23?,26-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.43E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499613
PNG
(CHEMBL3739974)
Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C36H45N6O9P/c37-20-8-7-14-28(36(47)42-21-9-15-31(42)35(46)40-29(32(38)43)22-24-10-3-1-4-11-24)39-34(45)30(41-33(44)26-12-5-2-6-13-26)23-25-16-18-27(19-17-25)51-52(48,49)50/h1-6,10-13,16-19,28-31H,7-9,14-15,20-23,37H2,(H2,38,43)(H,39,45)(H,40,46)(H,41,44)(H2,48,49,50)/t28-,29-,30-,31-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499603
PNG
(CHEMBL3740899)
Show SMILES NCCCC[C@H](NC(=O)c1cc2cc(OP(O)(O)=O)ccc2[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C29H37N6O8P/c30-13-5-4-9-22(33-27(37)24-17-19-16-20(43-44(40,41)42)11-12-21(19)32-24)29(39)35-14-6-10-25(35)28(38)34-23(26(31)36)15-18-7-2-1-3-8-18/h1-3,7-8,11-12,16-17,22-23,25,32H,4-6,9-10,13-15,30H2,(H2,31,36)(H,33,37)(H,34,38)(H2,40,41,42)/t22-,23-,25-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499601
PNG
(CHEMBL3740037)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(C)(C)C |r|
Show InChI InChI=1S/C31H42N5O9P/c1-19(37)33-24(18-21-12-14-22(15-13-21)45-46(42,43)44)28(39)35-26(31(2,3)4)30(41)36-16-8-11-25(36)29(40)34-23(27(32)38)17-20-9-6-5-7-10-20/h5-7,9-10,12-15,23-26H,8,11,16-18H2,1-4H3,(H2,32,38)(H,33,37)(H,34,40)(H,35,39)(H2,42,43,44)/t23-,24-,25-,26+/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499602
PNG
(CHEMBL3741973)
Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C37H47N6O9P/c38-20-8-7-14-29(37(48)43-21-9-15-32(43)36(47)42-30(34(39)45)22-25-10-3-1-4-11-25)41-35(46)31(40-33(44)24-26-12-5-2-6-13-26)23-27-16-18-28(19-17-27)52-53(49,50)51/h1-6,10-13,16-19,29-32H,7-9,14-15,20-24,38H2,(H2,39,45)(H,40,44)(H,41,46)(H,42,47)(H2,49,50,51)/t29-,30-,31-,32-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499619
PNG
(CHEMBL3741753)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(N)=O |r|
Show InChI InChI=1S/C36H51N8O11P/c1-22(45)40-28(21-24-12-14-25(15-13-24)55-56(52,53)54)33(48)42-27(10-5-6-18-37)36(51)44-19-7-11-30(44)35(50)43-29(20-23-8-3-2-4-9-23)34(49)41-26(32(39)47)16-17-31(38)46/h2-4,8-9,12-15,26-30H,5-7,10-11,16-21,37H2,1H3,(H2,38,46)(H2,39,47)(H,40,45)(H,41,49)(H,42,48)(H,43,50)(H2,52,53,54)/t26-,27-,28-,29-,30-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499599
PNG
(CHEMBL3739898)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r|
Show InChI InChI=1S/C40H56N9O14P/c1-23(50)44-30(21-25-12-14-26(15-13-25)63-64(60,61)62)37(56)46-28(10-5-6-18-41)40(59)49-19-7-11-32(49)39(58)48-31(20-24-8-3-2-4-9-24)38(57)45-27(16-17-33(42)51)36(55)47-29(35(43)54)22-34(52)53/h2-4,8-9,12-15,27-32H,5-7,10-11,16-22,41H2,1H3,(H2,42,51)(H2,43,54)(H,44,50)(H,45,57)(H,46,56)(H,47,55)(H,48,58)(H,52,53)(H2,60,61,62)/t27-,28-,29-,30-,31-,32-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499600
PNG
(CHEMBL3740866)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(N)=O |r|
Show InChI InChI=1S/C22H34N5O8P/c1-14(28)25-18(13-15-7-9-16(10-8-15)35-36(32,33)34)21(30)26-17(5-2-3-11-23)22(31)27-12-4-6-19(27)20(24)29/h7-10,17-19H,2-6,11-13,23H2,1H3,(H2,24,29)(H,25,28)(H,26,30)(H2,32,33,34)/t17-,18-,19-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499632
PNG
(CHEMBL3739902)
Show SMILES CCCC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C31H42N5O9P/c1-3-4-11-24(34-29(39)26(33-20(2)37)19-22-13-15-23(16-14-22)45-46(42,43)44)31(41)36-17-8-12-27(36)30(40)35-25(28(32)38)18-21-9-6-5-7-10-21/h5-7,9-10,13-16,24-27H,3-4,8,11-12,17-19H2,1-2H3,(H2,32,38)(H,33,37)(H,34,39)(H,35,40)(H2,42,43,44)/t24-,25-,26-,27-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499621
PNG
(CHEMBL3741480)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C31H43N6O9P/c1-20(38)34-26(19-22-12-14-23(15-13-22)46-47(43,44)45)29(40)35-24(10-5-6-16-32)31(42)37-17-7-11-27(37)30(41)36-25(28(33)39)18-21-8-3-2-4-9-21/h2-4,8-9,12-15,24-27H,5-7,10-11,16-19,32H2,1H3,(H2,33,39)(H,34,38)(H,35,40)(H,36,41)(H2,43,44,45)/t24-,25-,26-,27-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499628
PNG
(CHEMBL3740092)
Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)\C=C\c1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C38H47N6O9P/c39-22-8-7-14-30(38(49)44-23-9-15-33(44)37(48)43-31(35(40)46)24-27-12-5-2-6-13-27)42-36(47)32(41-34(45)21-18-26-10-3-1-4-11-26)25-28-16-19-29(20-17-28)53-54(50,51)52/h1-6,10-13,16-21,30-33H,7-9,14-15,22-25,39H2,(H2,40,46)(H,41,45)(H,42,47)(H,43,48)(H2,50,51,52)/b21-18+/t30-,31-,32-,33-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499617
PNG
(CHEMBL3740777)
Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C38H49N6O9P/c39-22-8-7-14-30(38(49)44-23-9-15-33(44)37(48)43-31(35(40)46)24-27-12-5-2-6-13-27)42-36(47)32(41-34(45)21-18-26-10-3-1-4-11-26)25-28-16-19-29(20-17-28)53-54(50,51)52/h1-6,10-13,16-17,19-20,30-33H,7-9,14-15,18,21-25,39H2,(H2,40,46)(H,41,45)(H,42,47)(H,43,48)(H2,50,51,52)/t30-,31-,32-,33-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.10E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499623
PNG
(CHEMBL3742329)
Show SMILES NCCCC[C@H](NC(=O)\C=C\c1ccc(OP(O)(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C29H38N5O8P/c30-17-5-4-9-23(32-26(35)16-13-20-11-14-22(15-12-20)42-43(39,40)41)29(38)34-18-6-10-25(34)28(37)33-24(27(31)36)19-21-7-2-1-3-8-21/h1-3,7-8,11-16,23-25H,4-6,9-10,17-19,30H2,(H2,31,36)(H,32,35)(H,33,37)(H2,39,40,41)/b16-13+/t23-,24-,25-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499622
PNG
(CHEMBL3740842)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C28H36N5O9P/c1-17(30-26(36)23(31-18(2)34)16-20-10-12-21(13-11-20)42-43(39,40)41)28(38)33-14-6-9-24(33)27(37)32-22(25(29)35)15-19-7-4-3-5-8-19/h3-5,7-8,10-13,17,22-24H,6,9,14-16H2,1-2H3,(H2,29,35)(H,30,36)(H,31,34)(H,32,37)(H2,39,40,41)/t17-,22-,23-,24-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.49E+4n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))		BDBM50499615
PNG
(CHEMBL3740751)
Show SMILES NCCCC[C@H](NC(=O)c1cc2cc(OP(O)(O)=O)ccc2o1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Show InChI InChI=1S/C29H36N5O9P/c30-13-5-4-9-21(32-28(37)25-17-19-16-20(43-44(39,40)41)11-12-24(19)42-25)29(38)34-14-6-10-23(34)27(36)33-22(26(31)35)15-18-7-2-1-3-8-18/h1-3,7-8,11-12,16-17,21-23H,4-6,9-10,13-15,30H2,(H2,31,35)(H,32,37)(H,33,36)(H2,39,40,41)/t21-,22-,23-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.96E+4n/an/an/an/an/an/a



Rice University

Curated by ChEMBL


Assay Description
Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...

J Med Chem 58: 8970-84 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01321
BindingDB Entry DOI: 10.7270/Q2TQ64KV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%