Affinity Data by PubMed id=26510670

PubMed code 26510670

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133608 (CHEMBL3633470) Show SMILES CC(C)(C)CCOC(=O)Nc1ccccc1C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133607 (CHEMBL3633471) Show SMILES CC(C)(C)CCOC(=O)Nc1ccc(cc1)C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133605 (CHEMBL3633473) Show SMILES C[Si](C)(C)CCOC(=O)Nc1ccc(cc1)C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133606 (CHEMBL3633472) Show SMILES C[Si](C)(C)CCOC(=O)Nc1ccccc1C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133611 (CHEMBL3633467) Show SMILES CC(C)(C)CCOC(=O)Oc1ccc(cc1)C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133609 (CHEMBL3633469) Show SMILES C[Si](C)(C)CCOC(=O)Oc1ccc(cc1)C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133610 (CHEMBL3633468) Show SMILES C[Si](C)(C)CCOC(=O)Oc1ccccc1C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50133612 (CHEMBL3633466) Show SMILES CC(C)(C)CCOC(=O)Oc1ccccc1C#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lehigh University Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholineiodide as substrate measured at 30 secs intervals over 9 mins by E...				Bioorg Med Chem Lett 25: 5609-12 (2015) Article DOI: 10.1016/j.bmcl.2015.10.039 BindingDB Entry DOI: 10.7270/Q2NZ89FR
Lehigh University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%